No evidence of association between genetic variants of the PDCD1 ligands and SLE

PDCD1, an immunoreceptor involved in peripheral tolerance has previously been shown to be genetically associated with systemic lupus erythematosus (SLE). PDCD1 has two ligands whose genes are located in close proximity on chromosome 9p24. Our attention was drawn to these ligands after finding sugges...

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Veröffentlicht in:	Genes and immunity 2007-01, Vol.8 (1), p.69-74
Hauptverfasser:	Abelson, A K, Johansson, C M, Kozyrev, S V, Kristjansdottir, H, Gunnarsson, I, Svenungsson, E, Jönsen, A, Lima, G, Scherbarth, H R, Gamron, S, Allievi, A, Palatnik, S A, Alvarellos, A, Paira, S, Graf, C, Guillerón, C, Catoggio, L J, Prigione, C, Battagliotti, C G, Berbotto, G A, García, M A, Perandones, C E, Truedsson, L, Steinsson, K, Sturfelt, G, Pons-Estel, B, Alarcón-Riquelme, M E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - genetics Antigens, CD - metabolism Apoptosis Regulatory Proteins - metabolism autoimmunity B7-H1 Antigen Biomedical and Life Sciences Biomedicine Cancer Research Chromosome 9 Chromosomes Clinical Medicine Collaboration Dendritic cells Female Gene Expression Genes Genetic aspects genetic association Genetic diversity Genetic engineering Genetic polymorphisms Genetic Predisposition to Disease Genomes Haplotypes Human Genetics Humans Immunology Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - metabolism Klinisk medicin Ligands Linkage Disequilibrium Lupus Lupus Erythematosus, Systemic - genetics Male Medical and Health Sciences MEDICIN Medicin och hälsovetenskap MEDICINE original-article PD-L1 PD-L2 Polymorphism, Single Nucleotide Programmed Cell Death 1 Ligand 2 Protein Programmed Cell Death 1 Receptor Reumatologi och inflammation Rheumatology Rheumatology and Autoimmunity Risk factors Single-nucleotide polymorphism Systemic lupus erythematosus
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