The prevalence of neuropathic pain after non-traumatic spinal cord lesion
Study design: Retrospective register study. Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aet...
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creator | Werhagen, L Hultling, C Molander, C |
description | Study design:
Retrospective register study.
Objective:
To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology.
Setting:
A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden.
Method:
All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with
χ
2
– analysis and logistic regression.
Results:
In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence.
Conclusion:
Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life. |
doi_str_mv | 10.1038/sj.sc.3102000 |
format | Article |
fullrecord | <record><control><sourceid>proquest_swepu</sourceid><recordid>TN_cdi_swepub_primary_oai_swepub_ki_se_572570</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>904462734</sourcerecordid><originalsourceid>FETCH-LOGICAL-c629t-f6dbf1fad192251c6787d7fab769196d257c7becdf17f66eb4049facbf168f2d3</originalsourceid><addsrcrecordid>eNp9ks1v1DAQxS0EoqVw5AiKkIADymI7iR0fq_JVqRKXwtVy7HHrJWsHOwbx3-PVpo2EtJw88vzem6fRIPSc4A3BTf8-bTdJbxqCKcb4ATolLWd1x2j7sNQNo3XbiOYEPUlpWwBBRP8YnRBOGMa8O0WX17dQTRF-qRG8hirYykOOYVLzrdPVpJyvlJ0hVj74eo4q79RcGmlyXo2VDtFUIyQX_FP0yKoxwbPlPUPfPn28vvhSX339fHlxflVrRsVcW2YGS6wyRFDaEc14zw23auCshGOGdlzzAbSxhFvGYGhxK6zSRcR6S01zhuqDb_oNUx7kFN1OxT8yKCeXrx-lAtnx4oULL47yUwxmFd0JCekEZn3Pi_bdUe0H9_1chngjc5aEY0YK_fZAF9ufGdIsdy5pGEflIeQkBW5bRnnTFvLNf0nW04I2-wCv_gG3Icey-SQpFQ0jXLTrRnQMKUWw9zkJlvsjkWkrk5bLkRT-5WKahx2YlV6uogCvF0AlrUYbldcurZzAPe_xPt1mWU9p-RuIa7pjk18cBF7NOcK9413_L_qh33E</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>229361794</pqid></control><display><type>article</type><title>The prevalence of neuropathic pain after non-traumatic spinal cord lesion</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Werhagen, L ; Hultling, C ; Molander, C</creator><creatorcontrib>Werhagen, L ; Hultling, C ; Molander, C</creatorcontrib><description>Study design:
Retrospective register study.
Objective:
To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology.
Setting:
A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden.
Method:
All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with
χ
2
– analysis and logistic regression.
Results:
In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence.
Conclusion:
Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life.</description><identifier>ISSN: 1362-4393</identifier><identifier>ISSN: 1476-5624</identifier><identifier>EISSN: 1476-5624</identifier><identifier>DOI: 10.1038/sj.sc.3102000</identifier><identifier>PMID: 17160075</identifier><identifier>CODEN: SPCOFM</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anatomy ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Cerebrospinal fluid. Meninges. Spinal cord ; Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves ; Child ; Child, Preschool ; Comorbidity ; Female ; Human Physiology ; Humans ; Infant ; Infant, Newborn ; Injuries of the nervous system and the skull. Diseases due to physical agents ; Male ; Medical sciences ; MEDICIN ; Medicin och hälsovetenskap ; MEDICINE ; Middle Aged ; Nervous system (semeiology, syndromes) ; neuralgia ; Neuralgia - epidemiology ; Neurochemistry ; Neurology ; Neuropsychology ; Neurosciences ; Neurosurgery ; non-traumatic spinal cord lesion ; original-article ; pain ; Prevalence ; Registries ; rehabilitation ; Risk Assessment - methods ; Risk Factors ; Spinal Cord Diseases - epidemiology ; Spinal Cord Injuries - classification ; Spinal Cord Injuries - epidemiology ; Spinal Diseases - epidemiology ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Sweden - epidemiology ; Traumas. Diseases due to physical agents</subject><ispartof>Spinal cord, 2007-09, Vol.45 (9), p.609-615</ispartof><rights>Springer Nature Limited 2006</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Nature Publishing Group Sep 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c629t-f6dbf1fad192251c6787d7fab769196d257c7becdf17f66eb4049facbf168f2d3</citedby><cites>FETCH-LOGICAL-c629t-f6dbf1fad192251c6787d7fab769196d257c7becdf17f66eb4049facbf168f2d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19087807$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17160075$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-17061$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:115906887$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Werhagen, L</creatorcontrib><creatorcontrib>Hultling, C</creatorcontrib><creatorcontrib>Molander, C</creatorcontrib><title>The prevalence of neuropathic pain after non-traumatic spinal cord lesion</title><title>Spinal cord</title><addtitle>Spinal Cord</addtitle><addtitle>Spinal Cord</addtitle><description>Study design:
Retrospective register study.
Objective:
To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology.
Setting:
A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden.
Method:
All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with
χ
2
– analysis and logistic regression.
Results:
In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence.
Conclusion:
Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anatomy</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cerebrospinal fluid. Meninges. Spinal cord</subject><subject>Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Comorbidity</subject><subject>Female</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Injuries of the nervous system and the skull. Diseases due to physical agents</subject><subject>Male</subject><subject>Medical sciences</subject><subject>MEDICIN</subject><subject>Medicin och hälsovetenskap</subject><subject>MEDICINE</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>neuralgia</subject><subject>Neuralgia - epidemiology</subject><subject>Neurochemistry</subject><subject>Neurology</subject><subject>Neuropsychology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>non-traumatic spinal cord lesion</subject><subject>original-article</subject><subject>pain</subject><subject>Prevalence</subject><subject>Registries</subject><subject>rehabilitation</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Spinal Cord Diseases - epidemiology</subject><subject>Spinal Cord Injuries - classification</subject><subject>Spinal Cord Injuries - epidemiology</subject><subject>Spinal Diseases - epidemiology</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Sweden - epidemiology</subject><subject>Traumas. Diseases due to physical agents</subject><issn>1362-4393</issn><issn>1476-5624</issn><issn>1476-5624</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9ks1v1DAQxS0EoqVw5AiKkIADymI7iR0fq_JVqRKXwtVy7HHrJWsHOwbx3-PVpo2EtJw88vzem6fRIPSc4A3BTf8-bTdJbxqCKcb4ATolLWd1x2j7sNQNo3XbiOYEPUlpWwBBRP8YnRBOGMa8O0WX17dQTRF-qRG8hirYykOOYVLzrdPVpJyvlJ0hVj74eo4q79RcGmlyXo2VDtFUIyQX_FP0yKoxwbPlPUPfPn28vvhSX339fHlxflVrRsVcW2YGS6wyRFDaEc14zw23auCshGOGdlzzAbSxhFvGYGhxK6zSRcR6S01zhuqDb_oNUx7kFN1OxT8yKCeXrx-lAtnx4oULL47yUwxmFd0JCekEZn3Pi_bdUe0H9_1chngjc5aEY0YK_fZAF9ufGdIsdy5pGEflIeQkBW5bRnnTFvLNf0nW04I2-wCv_gG3Icey-SQpFQ0jXLTrRnQMKUWw9zkJlvsjkWkrk5bLkRT-5WKahx2YlV6uogCvF0AlrUYbldcurZzAPe_xPt1mWU9p-RuIa7pjk18cBF7NOcK9413_L_qh33E</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>Werhagen, L</creator><creator>Hultling, C</creator><creator>Molander, C</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>DF2</scope></search><sort><creationdate>20070901</creationdate><title>The prevalence of neuropathic pain after non-traumatic spinal cord lesion</title><author>Werhagen, L ; Hultling, C ; Molander, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c629t-f6dbf1fad192251c6787d7fab769196d257c7becdf17f66eb4049facbf168f2d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anatomy</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cerebrospinal fluid. Meninges. Spinal cord</topic><topic>Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Comorbidity</topic><topic>Female</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Injuries of the nervous system and the skull. Diseases due to physical agents</topic><topic>Male</topic><topic>Medical sciences</topic><topic>MEDICIN</topic><topic>Medicin och hälsovetenskap</topic><topic>MEDICINE</topic><topic>Middle Aged</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>neuralgia</topic><topic>Neuralgia - epidemiology</topic><topic>Neurochemistry</topic><topic>Neurology</topic><topic>Neuropsychology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>non-traumatic spinal cord lesion</topic><topic>original-article</topic><topic>pain</topic><topic>Prevalence</topic><topic>Registries</topic><topic>rehabilitation</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Spinal Cord Diseases - epidemiology</topic><topic>Spinal Cord Injuries - classification</topic><topic>Spinal Cord Injuries - epidemiology</topic><topic>Spinal Diseases - epidemiology</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Sweden - epidemiology</topic><topic>Traumas. Diseases due to physical agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Werhagen, L</creatorcontrib><creatorcontrib>Hultling, C</creatorcontrib><creatorcontrib>Molander, C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Uppsala universitet</collection><jtitle>Spinal cord</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Werhagen, L</au><au>Hultling, C</au><au>Molander, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence of neuropathic pain after non-traumatic spinal cord lesion</atitle><jtitle>Spinal cord</jtitle><stitle>Spinal Cord</stitle><addtitle>Spinal Cord</addtitle><date>2007-09-01</date><risdate>2007</risdate><volume>45</volume><issue>9</issue><spage>609</spage><epage>615</epage><pages>609-615</pages><issn>1362-4393</issn><issn>1476-5624</issn><eissn>1476-5624</eissn><coden>SPCOFM</coden><abstract>Study design:
Retrospective register study.
Objective:
To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology.
Setting:
A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden.
Method:
All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with
χ
2
– analysis and logistic regression.
Results:
In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence.
Conclusion:
Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>17160075</pmid><doi>10.1038/sj.sc.3102000</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Anatomy Biological and medical sciences Biomedical and Life Sciences Biomedicine Cerebrospinal fluid. Meninges. Spinal cord Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves Child Child, Preschool Comorbidity Female Human Physiology Humans Infant Infant, Newborn Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences MEDICIN Medicin och hälsovetenskap MEDICINE Middle Aged Nervous system (semeiology, syndromes) neuralgia Neuralgia - epidemiology Neurochemistry Neurology Neuropsychology Neurosciences Neurosurgery non-traumatic spinal cord lesion original-article pain Prevalence Registries rehabilitation Risk Assessment - methods Risk Factors Spinal Cord Diseases - epidemiology Spinal Cord Injuries - classification Spinal Cord Injuries - epidemiology Spinal Diseases - epidemiology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Sweden - epidemiology Traumas. Diseases due to physical agents |
title | The prevalence of neuropathic pain after non-traumatic spinal cord lesion |
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