The prevalence of neuropathic pain after non-traumatic spinal cord lesion

Study design: Retrospective register study. Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aet...

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Veröffentlicht in:Spinal cord 2007-09, Vol.45 (9), p.609-615
Hauptverfasser: Werhagen, L, Hultling, C, Molander, C
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description Study design: Retrospective register study. Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology. Setting: A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden. Method: All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with χ 2 – analysis and logistic regression. Results: In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence. Conclusion: Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life.
doi_str_mv 10.1038/sj.sc.3102000
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Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology. Setting: A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden. Method: All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with χ 2 – analysis and logistic regression. Results: In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence. 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Diseases due to physical agents ; Male ; Medical sciences ; MEDICIN ; Medicin och hälsovetenskap ; MEDICINE ; Middle Aged ; Nervous system (semeiology, syndromes) ; neuralgia ; Neuralgia - epidemiology ; Neurochemistry ; Neurology ; Neuropsychology ; Neurosciences ; Neurosurgery ; non-traumatic spinal cord lesion ; original-article ; pain ; Prevalence ; Registries ; rehabilitation ; Risk Assessment - methods ; Risk Factors ; Spinal Cord Diseases - epidemiology ; Spinal Cord Injuries - classification ; Spinal Cord Injuries - epidemiology ; Spinal Diseases - epidemiology ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Sweden - epidemiology ; Traumas. 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Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology. Setting: A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden. Method: All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with χ 2 – analysis and logistic regression. Results: In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence. Conclusion: Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anatomy</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cerebrospinal fluid. Meninges. Spinal cord</subject><subject>Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Comorbidity</subject><subject>Female</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Injuries of the nervous system and the skull. Diseases due to physical agents</subject><subject>Male</subject><subject>Medical sciences</subject><subject>MEDICIN</subject><subject>Medicin och hälsovetenskap</subject><subject>MEDICINE</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>neuralgia</subject><subject>Neuralgia - epidemiology</subject><subject>Neurochemistry</subject><subject>Neurology</subject><subject>Neuropsychology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>non-traumatic spinal cord lesion</subject><subject>original-article</subject><subject>pain</subject><subject>Prevalence</subject><subject>Registries</subject><subject>rehabilitation</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Spinal Cord Diseases - epidemiology</subject><subject>Spinal Cord Injuries - classification</subject><subject>Spinal Cord Injuries - epidemiology</subject><subject>Spinal Diseases - epidemiology</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Sweden - epidemiology</subject><subject>Traumas. 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Objective: To investigate the predictive value of the following parameters for the development of neuropathic pain after non-traumatic spinal cord lesion: that is age at onset of spinal cord disease, gender, completeness of lesion, level of lesion, and aetiology. Setting: A unit for patients with post-acute traumatic and non-traumatic spinal cord lesions in the greater area of Stockholm, Sweden. Method: All patients with non-traumatic spinal cord lesions visiting the unit between 1995 and 2000 were classified according to the following: that is neuropathic pain at or below lesion level according to IASP criteria, age at time of the onset of the spinal cord symptoms, injury level, complete/incomplete injury, and aetiology. Results were analysed with χ 2 – analysis and logistic regression. Results: In total, 38% had neuropathic pain, 15% had pain predominantly at the level of lesion, and 23% predominantly below the level of lesion. Of those with pain, 67% reported that the pain affected daily life. Women reported neuropathic pain below the level of lesion more often (40%) than men (13%). The prevalence was particularly high (64%) for patients with malignant spinal cord diseases. Neither age at onset of the spinal cord symptoms, nor complete/incomplete injury nor injury level had significant influence on the prevalence. Conclusion: Neuropathic pain is common among patients with acquired non-traumatic spinal cord lesions regardless of aetiology, often causing severe problems in daily life.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>17160075</pmid><doi>10.1038/sj.sc.3102000</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Aged
Aged, 80 and over
Anatomy
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cerebrospinal fluid. Meninges. Spinal cord
Cerebrospinal fluid. Spinal cord. Spinal roots. Spinal nerves
Child
Child, Preschool
Comorbidity
Female
Human Physiology
Humans
Infant
Infant, Newborn
Injuries of the nervous system and the skull. Diseases due to physical agents
Male
Medical sciences
MEDICIN
Medicin och hälsovetenskap
MEDICINE
Middle Aged
Nervous system (semeiology, syndromes)
neuralgia
Neuralgia - epidemiology
Neurochemistry
Neurology
Neuropsychology
Neurosciences
Neurosurgery
non-traumatic spinal cord lesion
original-article
pain
Prevalence
Registries
rehabilitation
Risk Assessment - methods
Risk Factors
Spinal Cord Diseases - epidemiology
Spinal Cord Injuries - classification
Spinal Cord Injuries - epidemiology
Spinal Diseases - epidemiology
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Sweden - epidemiology
Traumas. Diseases due to physical agents
title The prevalence of neuropathic pain after non-traumatic spinal cord lesion
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