Analytical performance and clinical utility of the INNOTEST® PHOSPHO-TAU(181P) assay for discrimination between Alzheimer's disease and dementia with Lewy bodies

Background: Total tau (T-tau) and β-amyloid(1-42) (Aβ1-42) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia. Differential diagnosis from dementia with Lewy bodies (DLB) in clinical settings is difficult. Methods: The...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2006-12, Vol.44 (12), p.1472-1480
Hauptverfasser:	Vanderstichele, Hugo, De Vreese, Karen, Blennow, Kaj, Andreasen, Niels, Sindic, Christian, Ivanoiu, Adrian, Hampel, Harald, Bürger, Katharina, Parnetti, Lucilla, Lanari, Alessia, Padovani, Allesandro, DiLuca, Monica, Bläser, Miriam, Ohrfelt Olsson, Annika, Pottel, Hans, Hulstaert, Frank, Vanmechelen, Eugeen
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Biological and medical sciences cerebrospinal fluid dementia diagnosis General aspects Investigative techniques, diagnostic techniques (general aspects) Medical sciences P-tau P-tau181P
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