Increase in CD30 ligand/CD153 and TNF-alpha expressing mast cells in basal cell carcinoma

Mast cells are a significant source of tumor necrosis factor (TNF) superfamily members, such as TNF-alpha, CD30 ligand/CD153 (CD30L) and CD40L/CD154. Furthermore, the expression of some of these proteins in mast cells has been associated with tumorigenesis, and mast cells have been found to be incre...

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Veröffentlicht in:	CANCER IMMUNOLOGY IMMUNOTHERAPY 2007-09, Vol.56 (9), p.1407-1415
Hauptverfasser:	Diaconu, Nicolae-Costin, Kaminska, Renata, Naukkarinen, Anita, Harvima, Rauno J, Nilsson, Gunnar, Harvima, Ilkka T
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Basal cell carcinoma Carcinoma, Basal Cell - immunology CD30 antigen CD30 Ligand - metabolism CD40 antigen CD40L protein Cell Proliferation Dermis Epithelium Female Humans Immunohistochemistry Immunoreactivity Ki-1 Antigen - metabolism Lesions Ligands Male Mast cells Mast Cells - cytology Mast Cells - immunology MEDICIN MEDICINE Middle Aged Original Skin cancer Skin diseases Skin Neoplasms - immunology Tumor necrosis factor receptors Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α Tumorigenesis
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