Pharmacokinetics of Levetiracetam during Pregnancy, Delivery, in the Neonatal Period, and Lactation

Purpose: To study pharmacokinetics of levetiracetam (LEV) during pregnancy, delivery, lactation, and in the neonatal period. Methods: Fourteen women with epilepsy receiving LEV treatment during pregnancy and lactation contributed with 15 pregnancies to this prospective study in which LEV concentrati...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2007-06, Vol.48 (6), p.1111-1116
Hauptverfasser:	Tomson, Torbjörn, Palm, Ragnar, Källén, Kristina, Ben‐Menachem, Elinor, Söderfeldt, Birgitta, Danielsson, Bo, Johansson, Rune, Luef, Gerhard, Öhman, Inger
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - analysis Anticonvulsants - pharmacokinetics Anticonvulsants - therapeutic use Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences birth Breast Feeding - adverse effects Breast milk Clinical Medicine Delivery, Obstetric - statistics & numerical data Delivery. Postpartum. Lactation Epilepsy Epilepsy - blood Epilepsy - drug therapy Epilepsy - metabolism Female Fetal Blood - chemistry Gynecology. Andrology. Obstetrics Half-Life Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Infant, Newborn - blood Infant, Newborn - metabolism Klinisk medicin Lactation - blood Lactation - metabolism Levetiracetam Maternal-Fetal Exchange - drug effects Medical and Health Sciences Medical sciences Medicin och hälsovetenskap Milk, Human - chemistry Milk, Human - metabolism Nervous system (semeiology, syndromes) Neurologi Neurology Neuropharmacology Pharmacokinetics Pharmacology. Drug treatments Piracetam - analogs & derivatives Piracetam - analysis Piracetam - pharmacokinetics Piracetam - therapeutic use Pregnancy Pregnancy Complications - blood Pregnancy Complications - drug therapy Pregnancy Complications - metabolism Pregnancy Trimester, Third - blood Pregnancy Trimester, Third - metabolism Prospective Studies Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Puerperal Disorders - blood Puerperal Disorders - drug therapy Puerperal Disorders - metabolism
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