Adenosine receptor–dopamine receptor interactions in the basal ganglia and their relevance for brain function

Abstract The dopamine D1 and D2 receptors are major receptors in the regulation of striatal function and striatal adenosine A1 and A2A receptors are major modulators of their signaling. The evidence suggests the existence of antagonistic A1 –D1 heteromeric receptor complexes in the basal ganglia and...

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