Expression of Erythropoietin Receptor and In vitro Functional Effects of Epoetins in B-Cell Malignancies

Purpose: Erythropoietin (EPO) and EPO receptor (EPO-R) expression have been reported in solid tumors and are claimed to regulate tumor growth; however, no data have been published on this issue in B-cell malignancies or normal lymphoid cells. This report describes genomic/protein EPO-R expression an...

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Veröffentlicht in:	Clinical cancer research 2007-06, Vol.13 (12), p.3536-3544
Hauptverfasser:	KOKHAEI, Parviz, ABDALLA, Amir Osman, HANSSON, Lotta, MIKAELSSON, Eva, KUBBIES, Manfred, HASELBECK, Anton, JERNBERG-WIKLUND, Helena, MELLSTEDT, Hakan, OSTERBORG, Anders
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antigens, CD - biosynthesis Antigens, Differentiation, T-Lymphocyte - biosynthesis Antineoplastic agents B-CLL Biological and medical sciences EPO-R erythropoietin Erythropoietin - metabolism Female Flow Cytometry Gene Expression Humans In Vitro Techniques Lectins, C-Type Leukemia, B-Cell - metabolism Lymphoma, Mantle-Cell - metabolism Male mantle-cell lymphoma Medical sciences MEDICIN Medicin och hälsovetenskap MEDICINE Middle Aged multiple myeloma Multiple Myeloma - metabolism Pharmacology. Drug treatments Receptors, Erythropoietin - biosynthesis Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis
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