The Impact of Truncation and Missing Family Links in Population-based Registers on Familial Risk Estimates

Family history information is often incomplete in population-based disease registers because of truncation and/or missing family links. In this study, the authors simulated complete populations of related individuals with realistic age, family structure, and incidence rates. After mimicking the real...

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Veröffentlicht in:	American journal of epidemiology 2007-12, Vol.166 (12), p.1461-1467
Hauptverfasser:	Leu, Monica, Czene, Kamila, Reilly, Marie
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis. Health state bias (epidemiology) Biological and medical sciences Breast Neoplasms - epidemiology Breast Neoplasms - genetics Computer Simulation Demography Epidemiologic Studies Epidemiology familial risk Families & family life Female Folkhälsovetenskap, global hälsa och socialmedicin General aspects Genetic disorders Genetic Predisposition to Disease - epidemiology Humans medical record linkage Medical research Medical sciences Miscellaneous missing data Population genetics Public Health, Global Health and Social Medicine Public health. Hygiene Public health. Hygiene-occupational medicine Registries Risk Assessment Risk factors Software Sweden
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