FMS-like tyrosine kinase 3 interacts with the glucocorticoid receptor complex and affects glucocorticoid dependent signaling

The glucocorticoid receptor (GR) forms part of a multiprotein complex consisting of chaperones and proteins active in glucocorticoid signaling and other pathways. By immunoaffinity purification of GR, followed by Edman sequencing and Western blotting, we identified the FMS-like tyrosine kinase 3 (Fl...

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Veröffentlicht in:	Biochemical and biophysical research communications 2008-04, Vol.368 (3), p.569-574
Hauptverfasser:	Asadi, Abolfazl, Hedman, Erik, Widén, Christina, Zilliacus, Johanna, Gustafsson, Jan-Åke, Wikström, Ann-Charlotte
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Flt3 fms-Like Tyrosine Kinase 3 - metabolism Glucocorticoid receptor Glucocorticoids Glucocorticoids - metabolism GST-pull down Hepatocytes - metabolism Immunoprecipitation Medicin och hälsovetenskap Rats Receptors, Glucocorticoid - metabolism Signal Transduction - physiology
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