HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers

HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have been described in highly exposed, persistently seronegative (HEPS) individuals, but well controlled studies have not been performed. We performed a prospective, nested case-control study to examine the association of gen...

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Veröffentlicht in:	AIDS (London) 2008-03, Vol.22 (6), p.727-735
Hauptverfasser:	HIRBOD, Taha, KAUL, Rupert, MACDONALD, Kelly S, BROLIDEN, Kristina, REICHARD, Camilla, KIMANI, Joshua, NGUGI, Elizabeth, BWAYO, Job J, NAGELKERKE, Nico, HASSELROT, Klara, BING LI, MOSES, Stephen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Anti-Bacterial Agents - therapeutic use Antibodies, Viral - analysis Azithromycin - therapeutic use Biological and medical sciences Case-Control Studies Enzyme-Linked Immunosorbent Assay Female Herpes Genitalis - virology HIV Infections - immunology HIV Infections - prevention & control HIV Infections - virology HIV-1 - physiology Human immunodeficiency virus Human viral diseases Humans Immunity, Mucosal Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunoglobulin A - analysis Immunopathology Incidence Infectious diseases Interferon-gamma - immunology Kenya Logistic Models Medical sciences Middle Aged Neutralization Tests Risk Factors Sex Work T-Lymphocytes - immunology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virus Replication
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