Passive immunization protects cynomolgus macaques against Puumala hantavirus challenge

Hantaviruses cause two severe and often fatal human diseases: haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Presently, there is no effective prevention available for HFRS or HPS. Here, we studied the effect of passive immunization on the course of infection i...

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Veröffentlicht in:	Antiviral therapy 2008, Vol.13 (1), p.125-133
Hauptverfasser:	KLINGSTRÖM, Jonas, STOLTZ, Malin, HARDESTAM, Jonas, AHLM, Clas, LUNDKVIST, Ake
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antibodies, Viral - blood Antiviral agents Biological and medical sciences C-Reactive Protein - metabolism Creatinine - blood Cynomolgus Cytokines - blood Hantavirus Hemorrhagic Fever with Renal Syndrome - immunology Immunization, Passive Macaca Macaca fascicularis - immunology Macaca fascicularis - virology Medical sciences Nitric Oxide - blood Pharmacology. Drug treatments Puumala virus - immunology Time Factors Viremia - immunology
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