Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation
Objective: To investigate the effects of expanded cardiac rehabilitation with multifactorial interventions on metabolic and inflammatory markers, exercise performance and on established cardiovascular risk factors. Design: Single-centre prospective randomized controlled trial. Setting: A university...
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| Veröffentlicht in: | Clinical rehabilitation 2008-04, Vol.22 (4), p.306-318 |
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| creator | Plüss, C Edström Karlsson, M Rydell Wallen, NH Billing, E. Held, C. |
| description | Objective: To investigate the effects of expanded cardiac rehabilitation with multifactorial interventions on metabolic and inflammatory markers, exercise performance and on established cardiovascular risk factors.
Design: Single-centre prospective randomized controlled trial.
Setting: A university hospital.
Subjects: Two hundred and twenty-four patients with an acute myocardial infarction or patients undergoing coronary artery by-pass grafting.
Intervention: Patients were randomized to expanded cardiac rehabilitation including stress management, increased physical training, staying at a 'patient hotel' and cooking sessions, or to usual cardiac rehabilitation
Main measures: Biochemical risk markers and exercise performance; follow-up was one year.
Results: There were no significant differences between the two treatment groups in the changes of biochemical risk markers or in exercise performance. Thus, low-density lipoprotein (LDL)-cholesterol levels decreased from 3.00 (0.97) to 2.54 (0.66) mmol/L in the intervention group and from 3.20 (0.85) to 2.54 (0.63) mmol/L in the control group, fibrinogen levels decreased from 5.30 (2.00) to 4.25 (1.01) g/L in the intervention group and from 5.29 (1.89) to 4.33 (0.83) g/L in the control group and C-reactive protein (CRP) levels decreased from 3.04 (2.79) to 2.09 (2.13) mg/L in the intervention group and from 4.01 (3.49) to 2.39 (2.49) mg/L in the control group. Total workload (W) improved from 118 (35) to 136 (34) in the intervention group and from 117 (36) to 133 (39) in the control group.
Conclusion: There was no further significant benefit in biochemical risk markers or in exercise performance among patients undergoing the expanded rehabilitation as compared to the control group which received usual cardiac rehabilitation. |
| doi_str_mv | 10.1177/0269215507085379 |
| format | Article |
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Design: Single-centre prospective randomized controlled trial.
Setting: A university hospital.
Subjects: Two hundred and twenty-four patients with an acute myocardial infarction or patients undergoing coronary artery by-pass grafting.
Intervention: Patients were randomized to expanded cardiac rehabilitation including stress management, increased physical training, staying at a 'patient hotel' and cooking sessions, or to usual cardiac rehabilitation
Main measures: Biochemical risk markers and exercise performance; follow-up was one year.
Results: There were no significant differences between the two treatment groups in the changes of biochemical risk markers or in exercise performance. Thus, low-density lipoprotein (LDL)-cholesterol levels decreased from 3.00 (0.97) to 2.54 (0.66) mmol/L in the intervention group and from 3.20 (0.85) to 2.54 (0.63) mmol/L in the control group, fibrinogen levels decreased from 5.30 (2.00) to 4.25 (1.01) g/L in the intervention group and from 5.29 (1.89) to 4.33 (0.83) g/L in the control group and C-reactive protein (CRP) levels decreased from 3.04 (2.79) to 2.09 (2.13) mg/L in the intervention group and from 4.01 (3.49) to 2.39 (2.49) mg/L in the control group. Total workload (W) improved from 118 (35) to 136 (34) in the intervention group and from 117 (36) to 133 (39) in the control group.
Conclusion: There was no further significant benefit in biochemical risk markers or in exercise performance among patients undergoing the expanded rehabilitation as compared to the control group which received usual cardiac rehabilitation.</description><identifier>ISSN: 0269-2155</identifier><identifier>ISSN: 1477-0873</identifier><identifier>EISSN: 1477-0873</identifier><identifier>DOI: 10.1177/0269215507085379</identifier><identifier>PMID: 18390974</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Aged ; Analysis of Variance ; Biomarkers - metabolism ; Blood Glucose - metabolism ; Blood Pressure ; Body Mass Index ; C-Reactive Protein - metabolism ; Cardiology ; Cardiovascular disease ; Caring sciences ; Clinical trials ; Coronary Artery Bypass - rehabilitation ; Coronary vessels ; Diet ; Exercise Test ; Female ; Fibrinogen - metabolism ; Heart attacks ; Hospitals ; Humans ; INTERDISCIPLINARY RESEARCH AREAS ; Intervention ; Ischemia ; Lipids - blood ; Male ; MEDICIN ; Medicin och hälsovetenskap ; MEDICINE ; Metabolism ; Middle Aged ; Myocardial Infarction - metabolism ; Myocardial Infarction - physiopathology ; Myocardial Infarction - psychology ; Myocardial Infarction - rehabilitation ; Participation ; Patients ; Performance evaluation ; Prospective Studies ; Rehabilitation ; Risk Factors ; Smoking ; Stress, Psychological - therapy ; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN ; Vein & artery diseases ; Vårdvetenskap</subject><ispartof>Clinical rehabilitation, 2008-04, Vol.22 (4), p.306-318</ispartof><rights>SAGE Publications © Apr 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c521t-958eb9cd162c86dd475d55bd523f9a199cba7c5e422601117ee6bce07bd82493</citedby><cites>FETCH-LOGICAL-c521t-958eb9cd162c86dd475d55bd523f9a199cba7c5e422601117ee6bce07bd82493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0269215507085379$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0269215507085379$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>230,314,780,784,885,12846,21819,27924,27925,30999,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18390974$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-93$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110411$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:116943545$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Plüss, C Edström</creatorcontrib><creatorcontrib>Karlsson, M Rydell</creatorcontrib><creatorcontrib>Wallen, NH</creatorcontrib><creatorcontrib>Billing, E.</creatorcontrib><creatorcontrib>Held, C.</creatorcontrib><title>Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation</title><title>Clinical rehabilitation</title><addtitle>Clin Rehabil</addtitle><description>Objective: To investigate the effects of expanded cardiac rehabilitation with multifactorial interventions on metabolic and inflammatory markers, exercise performance and on established cardiovascular risk factors.
Design: Single-centre prospective randomized controlled trial.
Setting: A university hospital.
Subjects: Two hundred and twenty-four patients with an acute myocardial infarction or patients undergoing coronary artery by-pass grafting.
Intervention: Patients were randomized to expanded cardiac rehabilitation including stress management, increased physical training, staying at a 'patient hotel' and cooking sessions, or to usual cardiac rehabilitation
Main measures: Biochemical risk markers and exercise performance; follow-up was one year.
Results: There were no significant differences between the two treatment groups in the changes of biochemical risk markers or in exercise performance. Thus, low-density lipoprotein (LDL)-cholesterol levels decreased from 3.00 (0.97) to 2.54 (0.66) mmol/L in the intervention group and from 3.20 (0.85) to 2.54 (0.63) mmol/L in the control group, fibrinogen levels decreased from 5.30 (2.00) to 4.25 (1.01) g/L in the intervention group and from 5.29 (1.89) to 4.33 (0.83) g/L in the control group and C-reactive protein (CRP) levels decreased from 3.04 (2.79) to 2.09 (2.13) mg/L in the intervention group and from 4.01 (3.49) to 2.39 (2.49) mg/L in the control group. Total workload (W) improved from 118 (35) to 136 (34) in the intervention group and from 117 (36) to 133 (39) in the control group.
Conclusion: There was no further significant benefit in biochemical risk markers or in exercise performance among patients undergoing the expanded rehabilitation as compared to the control group which received usual cardiac rehabilitation.</description><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Biomarkers - metabolism</subject><subject>Blood Glucose - metabolism</subject><subject>Blood Pressure</subject><subject>Body Mass Index</subject><subject>C-Reactive Protein - metabolism</subject><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Caring sciences</subject><subject>Clinical trials</subject><subject>Coronary Artery Bypass - rehabilitation</subject><subject>Coronary vessels</subject><subject>Diet</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Fibrinogen - metabolism</subject><subject>Heart attacks</subject><subject>Hospitals</subject><subject>Humans</subject><subject>INTERDISCIPLINARY RESEARCH AREAS</subject><subject>Intervention</subject><subject>Ischemia</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>MEDICIN</subject><subject>Medicin och hälsovetenskap</subject><subject>MEDICINE</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - metabolism</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Myocardial Infarction - psychology</subject><subject>Myocardial Infarction - rehabilitation</subject><subject>Participation</subject><subject>Patients</subject><subject>Performance evaluation</subject><subject>Prospective Studies</subject><subject>Rehabilitation</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Stress, Psychological - therapy</subject><subject>TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN</subject><subject>Vein & artery diseases</subject><subject>Vårdvetenskap</subject><issn>0269-2155</issn><issn>1477-0873</issn><issn>1477-0873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkk9v1DAQxS0EokvhzglZHJCQCNhOHMfHqpQ_UiUuFVfLsSe7KZs42I5gPwtflkl3YVGlFaexPb_3xnoaQp5z9pZzpd4xUWvBpWSKNbJU-gFZ8UqpgjWqfEhWS7tY-mfkSUq3jLFGVPwxOeNNqZlW1Yr8uuo6cDnR0FE7Uvg52dGDp85G31tHI2xs22_7bHMfRjrFsI52GID2eME3GFGbI9iMoi7ExcS6OQMddmFvskW2s9HdGSwEdSGG0cYdtTEDlnZXTDYlitZdpmGCeDftKXnU2W2CZ4d6Tm4-XN1cfiquv3z8fHlxXTgpeC60bKDVzvNauKb2vlLSS9l6KcpOW661a61yEiohasYxN4C6dcBU6zEOXZ6TYm-bfsA0t2aK_YCfM8H25vD0DU9gZC2Z4Mjrkzzm44-iP0LOa12VspKofXNS-77_emFCXJt5RgWr-DLq9f_xtNkYXSL7as_iH77PkLIZ-uRgu7UjhDkZxaqmlHIxfXkPvA1zHDFhIxirG6W5QIjtIRdDShG6v7M5M8vumfu7h5IXB9-5HcAfBYdl-ydou4bj0JOGvwG9G-XY</recordid><startdate>20080401</startdate><enddate>20080401</enddate><creator>Plüss, C Edström</creator><creator>Karlsson, M Rydell</creator><creator>Wallen, NH</creator><creator>Billing, E.</creator><creator>Held, C.</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>DF4</scope><scope>DF2</scope></search><sort><creationdate>20080401</creationdate><title>Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation</title><author>Plüss, C Edström ; Karlsson, M Rydell ; Wallen, NH ; Billing, E. ; Held, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c521t-958eb9cd162c86dd475d55bd523f9a199cba7c5e422601117ee6bce07bd82493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Biomarkers - metabolism</topic><topic>Blood Glucose - metabolism</topic><topic>Blood Pressure</topic><topic>Body Mass Index</topic><topic>C-Reactive Protein - metabolism</topic><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Caring sciences</topic><topic>Clinical trials</topic><topic>Coronary Artery Bypass - rehabilitation</topic><topic>Coronary vessels</topic><topic>Diet</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Fibrinogen - metabolism</topic><topic>Heart attacks</topic><topic>Hospitals</topic><topic>Humans</topic><topic>INTERDISCIPLINARY RESEARCH AREAS</topic><topic>Intervention</topic><topic>Ischemia</topic><topic>Lipids - blood</topic><topic>Male</topic><topic>MEDICIN</topic><topic>Medicin och hälsovetenskap</topic><topic>MEDICINE</topic><topic>Metabolism</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - metabolism</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Myocardial Infarction - psychology</topic><topic>Myocardial Infarction - rehabilitation</topic><topic>Participation</topic><topic>Patients</topic><topic>Performance evaluation</topic><topic>Prospective Studies</topic><topic>Rehabilitation</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Stress, Psychological - therapy</topic><topic>TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN</topic><topic>Vein & artery diseases</topic><topic>Vårdvetenskap</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Plüss, C Edström</creatorcontrib><creatorcontrib>Karlsson, M Rydell</creatorcontrib><creatorcontrib>Wallen, NH</creatorcontrib><creatorcontrib>Billing, E.</creatorcontrib><creatorcontrib>Held, C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection【Remote access available】</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Complete (ProQuest Database)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Family Health Database (Proquest)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Health Management Database (Proquest)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>Social Science Database (ProQuest)</collection><collection>Sociology Database (ProQuest)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Sophiahemmet Högskola</collection><collection>SWEPUB Uppsala universitet</collection><jtitle>Clinical rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Plüss, C Edström</au><au>Karlsson, M Rydell</au><au>Wallen, NH</au><au>Billing, E.</au><au>Held, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation</atitle><jtitle>Clinical rehabilitation</jtitle><addtitle>Clin Rehabil</addtitle><date>2008-04-01</date><risdate>2008</risdate><volume>22</volume><issue>4</issue><spage>306</spage><epage>318</epage><pages>306-318</pages><issn>0269-2155</issn><issn>1477-0873</issn><eissn>1477-0873</eissn><abstract>Objective: To investigate the effects of expanded cardiac rehabilitation with multifactorial interventions on metabolic and inflammatory markers, exercise performance and on established cardiovascular risk factors.
Design: Single-centre prospective randomized controlled trial.
Setting: A university hospital.
Subjects: Two hundred and twenty-four patients with an acute myocardial infarction or patients undergoing coronary artery by-pass grafting.
Intervention: Patients were randomized to expanded cardiac rehabilitation including stress management, increased physical training, staying at a 'patient hotel' and cooking sessions, or to usual cardiac rehabilitation
Main measures: Biochemical risk markers and exercise performance; follow-up was one year.
Results: There were no significant differences between the two treatment groups in the changes of biochemical risk markers or in exercise performance. Thus, low-density lipoprotein (LDL)-cholesterol levels decreased from 3.00 (0.97) to 2.54 (0.66) mmol/L in the intervention group and from 3.20 (0.85) to 2.54 (0.63) mmol/L in the control group, fibrinogen levels decreased from 5.30 (2.00) to 4.25 (1.01) g/L in the intervention group and from 5.29 (1.89) to 4.33 (0.83) g/L in the control group and C-reactive protein (CRP) levels decreased from 3.04 (2.79) to 2.09 (2.13) mg/L in the intervention group and from 4.01 (3.49) to 2.39 (2.49) mg/L in the control group. Total workload (W) improved from 118 (35) to 136 (34) in the intervention group and from 117 (36) to 133 (39) in the control group.
Conclusion: There was no further significant benefit in biochemical risk markers or in exercise performance among patients undergoing the expanded rehabilitation as compared to the control group which received usual cardiac rehabilitation.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>18390974</pmid><doi>10.1177/0269215507085379</doi><tpages>13</tpages></addata></record> |
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| ispartof | Clinical rehabilitation, 2008-04, Vol.22 (4), p.306-318 |
| issn | 0269-2155 1477-0873 1477-0873 |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); SAGE Journals |
| subjects | Aged Analysis of Variance Biomarkers - metabolism Blood Glucose - metabolism Blood Pressure Body Mass Index C-Reactive Protein - metabolism Cardiology Cardiovascular disease Caring sciences Clinical trials Coronary Artery Bypass - rehabilitation Coronary vessels Diet Exercise Test Female Fibrinogen - metabolism Heart attacks Hospitals Humans INTERDISCIPLINARY RESEARCH AREAS Intervention Ischemia Lipids - blood Male MEDICIN Medicin och hälsovetenskap MEDICINE Metabolism Middle Aged Myocardial Infarction - metabolism Myocardial Infarction - physiopathology Myocardial Infarction - psychology Myocardial Infarction - rehabilitation Participation Patients Performance evaluation Prospective Studies Rehabilitation Risk Factors Smoking Stress, Psychological - therapy TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN Vein & artery diseases Vårdvetenskap |
| title | Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation |
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