Collaborative Pooled Analysis of Data on C-Reactive Protein Gene Variants and Coronary Disease: Judging Causality by Mendelian Randomisation

Many prospective studies have reported associations between circulating C-reactive protein (CRP) levels and risk of coronary heart disease (CHD), but causality remains uncertain. Studies of CHD are being conducted that involve measurement of common polymorphisms of the CRP gene known to be associate...

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Veröffentlicht in:	European journal of epidemiology 2008, Vol.23 (8), p.531-540
Hauptverfasser:	CRP CHD Genetics Collaboration, Danesh, J, Hingorani, A, ----------, ----, Hallmans, Göran
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Beräkningsmatematik Biological and medical sciences Blood tests C-Reactive Protein C-Reactive Protein - genetics C-Reactive Protein - metabolism Cardiology Cardiology. Vascular system Cardiovascular Disease Cardiovascular diseases Case-Control Studies Computational Mathematics Congenital heart defects Cooperative Behavior Coronary artery disease Coronary Disease Coronary Disease - epidemiology Coronary Disease - genetics Coronary heart disease Epidemiology General aspects Genetic Genetics Genotypes Haplotypes Heart Humans Infectious Diseases Inflammation Inflammation - genetics Medical genetics Medical Genetics and Genomics Medical sciences Medicine Medicine & Public Health Medicinsk genetik och genomik metabolism Miscellaneous Oncology Polymorphism Polymorphism, Genetic - genetics Predisposing factors Prospective studies Proteins Public Health Public health. Hygiene Public health. Hygiene-occupational medicine Research Design Risk factors
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