Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis

Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate gene for coronary heart disease (CHD). The authors assessed associations between 7 LPL polymorphisms and lipid fractions and CHD risk in population-based cohort, case-control, and cross-sectional studies publish...

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Veröffentlicht in:	American journal of epidemiology 2008-12, Vol.168 (11), p.1233-1246
Hauptverfasser:	Sagoo, Gurdeep S., Tatt, Iain, Salanti, Georgia, Butterworth, Adam S., Sarwar, Nadeem, van Maarle, Merel, Jukema, J. Wouter, Wiman, Björn, Kastelein, John J. P., Bennet, Anna M., de Faire, Ulf, Danesh, John, Higgins, Julian P. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Analysis. Health state Biological and medical sciences Cardiology. Vascular system Cardiovascular disease cholesterol Cholesterol, HDL - blood Cholesterol, HDL - genetics Confidence Intervals coronary disease Coronary Disease - blood Coronary Disease - enzymology Coronary Disease - epidemiology Coronary Disease - genetics Coronary heart disease Coronary Stenosis - genetics Disorders of blood lipids. Hyperlipoproteinemia Enzymes Epidemiology General aspects genetics Genomics Genotype HDL Heart Humans Lipids - blood lipoprotein lipase Lipoprotein Lipase - blood Lipoprotein Lipase - genetics Medical sciences Meta-analysis Metabolic diseases Metabolism Miscellaneous myocardial infarction Myocardial Infarction - genetics Odds Ratio Polymorphism, Genetic Public health. Hygiene Public health. Hygiene-occupational medicine triglycerides Triglycerides - blood Triglycerides - genetics United Kingdom - epidemiology
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