A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)

Abstract There is considerable evidence of altered glutamatergic signalling in schizophrenia and a polymorphic variant of the GRIK3 glutamate receptor gene on 1p34-33 has previously been associated to this psychotic disorder. We therefore conducted a systematic association study with 30 HapMap-selec...

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Veröffentlicht in:	Schizophrenia research 2009-02, Vol.107 (2), p.242-248
Hauptverfasser:	Djurovic, S, Kähler, A.K, Kulle, B, Jönsson, E.G, Agartz, I, Le Hellard, S, Hall, H, Jakobsen, K.D, Hansen, T, Melle, I, Werge, T, Steen, V.M, Andreassen, O.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Alleles Biological and medical sciences Candidate gene Chromosomes, Human, Pair 1 - genetics Female Genetic association Genetic Markers - genetics Genotype GluK3 Kainate Receptor Glutamate GRIK3 Haplotypes Humans Linkage Disequilibrium - genetics Male Medical sciences Middle Aged Polymorphism, Genetic - genetics Polymorphism, Single Nucleotide - genetics Psychiatric Status Rating Scales Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Psychotic Disorders - diagnosis Psychotic Disorders - genetics Psychotic Disorders - psychology Receptors, Kainic Acid - genetics Scandinavian and Nordic Countries Schizophrenia Schizophrenia - diagnosis Schizophrenia - genetics Schizophrenic Psychology
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