Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: results from a randomized trial

The purpose of this randomized study was to examine if goserelin concomitant to CMF-chemotherapy as adjuvant treatment for premenopausal breast cancer, protects the ovaries from premature failure. A total of 285 premenopausal breast cancer patients, in a randomized adjuvant trial (Zoladex in premeno...

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Veröffentlicht in:	Breast cancer research and treatment 2009-10, Vol.117 (3), p.561-567
Hauptverfasser:	Sverrisdottir, A, Nystedt, M, Johansson, H, Fornander, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Agents, Hormonal - administration & dosage Antineoplastic Combined Chemotherapy Protocols - administration & dosage Biological and medical sciences Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - pathology Cancer research Cancer therapies Chemotherapy, Adjuvant Clinical Trial Clinical trials Cyclophosphamide - administration & dosage Effects Female Female genital diseases Fluorouracil - administration & dosage Goserelin - administration & dosage Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Medicine Medicine & Public Health Methotrexate - administration & dosage Middle Aged Non tumoral diseases Oncology Ovarian Function Tests Ovary - drug effects Premenopause Primary Ovarian Insufficiency - prevention & control Reproductive system Tamoxifen - administration & dosage Tumors
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