Preoperative glucocorticoid administration attenuates the systemic stress response and hyperglycemia after surgical trauma in the rat

Abstract The stress response to surgery is characterized by activation of the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system, and by an inflammatory response and hyperglycemia. The aim of the present study was to investigate if preoperative corticosterone could reduce the pos...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2009-04, Vol.58 (4), p.449-455
Hauptverfasser:	Hager, Peter, Permert, Johan, Wikström, Ann-Charlotte, Herrington, Margery K, Östenson, Claes-Göran, Strömmer, Lisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Glucose - analysis Endocrinology & Metabolism Epinephrine - blood Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Glucocorticoids - administration & dosage Hydrocortisone - blood Hyperglycemia - prevention & control Insulin - blood Interleukin-10 - blood Interleukin-6 - blood Male Medicin och hälsovetenskap Norepinephrine - blood Rats Rats, Wistar Surgical Procedures, Operative - adverse effects Systemic Inflammatory Response Syndrome - prevention & control Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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