The rat as an animal model of Alzheimer's disease

• Introduction • The laboratory rat • Rat models of cholinergic‐clysfunction • Aβ‐based models of AD • Transgenic rats ‐ The TgAPPswe rat ‐ The UKUR25 rat ‐ The Tg6590 rat ‐ The triple transgenic rat ‐ The APP21 and APP31 transgenic rats ‐ The AD‐tau rat ‐ Transgenic rats – summary • Vi...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2009-06, Vol.13 (6), p.1034-1042
Hauptverfasser:	Benedikz, Eirikur, Kloskowska, Ewa, Winblad, Bengt
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer Disease - pathology Alzheimer's disease amyloid Amyloid beta-Protein Precursor - genetics Animal cognition Animal models Animals Animals, Genetically Modified Brain research cholinergic Disease Disease Models, Animal Genetics Genomes Humans Hypotheses Laboratories Medical research Memory Mutation Neurodegeneration Neurodegenerative diseases Pathology Peptides Physiology rat Rats Reviews Rodents Tau protein transgenic Transgenic animals Transgenic mice β-Amyloid
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