Adenosine, adenosine A 2A antagonists, and Parkinson's disease

Adenosine derived from the degradation of ATP/AMP functions as a signalling molecule in the nervous system through the occupation of A1, A2, and A3 adenosine receptors. Adenosine A 2A receptors have a selective localization to the basal ganglia and specifically to the indirect output pathway, and as...

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Veröffentlicht in:	Parkinsonism & related disorders 2009, Vol.15 (6), p.406-413
Hauptverfasser:	Jenner, P., Mori, A., Hauser, R., Morelli, M., Fredholm, B.B., Chen, J.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine - metabolism Adenosine A2 Receptor Antagonists Adenosine antagonists Animals Antiparkinson Agents - pharmacology Antiparkinson Agents - therapeutic use Basal Ganglia - drug effects Basal Ganglia - metabolism Basal Ganglia - pathology Clinical Trials as Topic Humans Medicin och hälsovetenskap Parkinson Disease - drug therapy Parkinson Disease - metabolism Parkinson Disease - pathology Parkinson's disease Purines - pharmacology Purines - therapeutic use Receptors, Purinergic P1 - metabolism
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