Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses

Summary Introduction Among sensitized infants, those with high, as compared with low levels, of salivary secretory IgA (SIgA) are less likely to develop allergic symptoms. Also, early colonization with certain gut microbiota, e.g. Lactobacilli and Bifidobacterium species, might be associated with le...

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Veröffentlicht in:	Clinical and experimental allergy 2009-12, Vol.39 (12), p.1842-1851
Hauptverfasser:	Sjögren, Y. M., Tomicic, S., Lundberg, A., Böttcher, M. F., Björkstén, B., Sverremark-Ekström, E., Jenmalm, M. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteroides fragilis Bacteroides fragilis - genetics Bacteroides fragilis - immunology Bacteroides fragilis - isolation & purification bifidobacteria Bifidobacterium - genetics Bifidobacterium - immunology Bifidobacterium - isolation & purification Biological and medical sciences Chemokine CCL4 - metabolism Child, Preschool Clostridium difficile Clostridium difficile - genetics Clostridium difficile - immunology Clostridium difficile - isolation & purification Feces - microbiology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression - genetics Gene Expression - immunology gut microbiota Humans Immune System - growth & development Immune System - immunology Immunity - immunology Immunity, Mucosal - immunology Immunoglobulin A, Secretory - immunology Infant Infant, Newborn Interferon-gamma - metabolism Interleukin-6 - metabolism Interleukins - metabolism Intestines - immunology Intestines - microbiology lactobacilli Lactobacillus - genetics Lactobacillus - immunology Lactobacillus - isolation & purification Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - metabolism Lipopolysaccharides - pharmacology Longitudinal Studies Male MEDICIN MEDICINE Metagenome - immunology Phytohemagglutinins - pharmacology Saliva - immunology SIgA TLR2 TLR4 Toll-Like Receptor 4 - genetics Tumor Necrosis Factor-alpha - metabolism
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