CSF neurochemicals during tryptophan depletion in individuals with remitted depression and healthy controls

Abstract The purpose of this study was to examine the differential effects of acute tryptophan (TRP) depletion vs. sham condition on plasma, cerebrospinal fluid (CSF) biochemical parameters, and mood in the following three subject groups: (1) nine antidepressant-free individuals with remitted depres...

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Veröffentlicht in:	European neuropsychopharmacology 2010-01, Vol.20 (1), p.18-24
Hauptverfasser:	Moreno, Francisco A, Parkinson, Damian, Palmer, Craig, Castro, Wm. Lesley, Misiaszek, John, El Khoury, Aram, Mathé, Aleksander A, Wright, Ron, Delgado, Pedro L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Case-Control Studies Cerebrospinal fluid (CSF) Chromatography, High Pressure Liquid - methods Circadian Rhythm - drug effects Cross-Over Studies Depressive Disorder, Major - cerebrospinal fluid Depressive Disorder, Major - drug therapy Double-Blind Method Electrochemistry - methods Female Homovanillic Acid - cerebrospinal fluid Humans Hydroxyindoleacetic Acid - cerebrospinal fluid Indoles - blood Indoles - cerebrospinal fluid Internal Medicine Male Methoxyhydroxyphenylglycol - cerebrospinal fluid Middle Aged Monoamine metabolites Neurochemistry Neuropeptide Y Neuropeptide Y - cerebrospinal fluid Paroxetine - pharmacology Paroxetine - therapeutic use Psychiatric Status Rating Scales Psychiatry Serotonin Uptake Inhibitors - pharmacology Serotonin Uptake Inhibitors - therapeutic use Sum of large neutral amino acids (ΣLNAA) Tryptophan - blood Tryptophan - cerebrospinal fluid Tryptophan - deficiency Tryptophan depletion Young Adult
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