Does abnormal insulin action or insulin secretion explain the increase in prevalence of impaired glucose metabolism with age in populations of different ethnicities?

Background Age is associated with both impaired glucose and insulin metabolism. To what extent the age‐related changes in insulin resistance (IR) and β‐cell function contribute to the increase in prevalence of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) is less known, and thi...

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Veröffentlicht in:	Diabetes/metabolism research and reviews 2010-05, Vol.26 (4), p.245-253
Hauptverfasser:	Ning, F., Qiao, Q., Tuomilehto, J., Hammar, N., Ho, S. Y., Söderberg, S., Zimmet, P. Z., Shaw, J. E., Nakagami, T., Mohan, V., Ramachandran, A., Lam, T. H., Andersson, S. W., Janus, E. D., Boyko, E. J., Fujimoto, W. Y., Pang, Z. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult age Age Factors Aged beta-cell function Biological and medical sciences Blood Glucose - metabolism deterioration Diabetes Mellitus, Type 2 - ethnology diabetes-mellitus Diabetes. Impaired glucose tolerance dysfunction Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance fasting glucose Female Fundamental and applied biological sciences. Psychology General aspects Glucose Intolerance - ethnology homeostasis model assessment Humans impaired fasting glucose impaired glucose tolerance Insulin - metabolism insulin resistance Insulin Resistance - ethnology Insulin Secretion Male Medical and Health Sciences Medical sciences Medicin och hälsovetenskap Middle Aged nondiabetic humans Prevalence Public health. Hygiene Public health. Hygiene-occupational medicine resistance sensitivity tolerance Vertebrates: endocrinology β-cell function
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