Once‐Daily Prolonged‐Release Tacrolimus (ADVAGRAF) Versus Twice‐Daily Tacrolimus (PROGRAF) in Liver Transplantation

The efficacy and safety of dual‐therapy regimens of twice‐daily tacrolimus (BID; Prograf) and once‐daily tacrolimus (QD; Advagraf) administered with steroids, without antibody induction, were compared in a multicenter, 1:1‐randomized, two‐arm, parallel‐group study in 475 primary liver transplant rec...

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Veröffentlicht in:	American journal of transplantation 2010-10, Vol.10 (10), p.2313-2323
Hauptverfasser:	Trunečka, P., Boillot, O., Seehofer, D., Pinna, A. D., Fischer, L., Ericzon, B.‐G., Troisi, R. I., Baccarani, U., Ortiz de Urbina, J., Wall, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Female Fundamental and applied biological sciences. Psychology Fundamental immunology Graft Rejection Hepatic transplantation Humans immunosuppression Immunosuppressive Agents - administration & dosage Kidney Function Tests Liver Transplantation - immunology Liver Transplantation - methods Liver, biliary tract, pancreas, portal circulation, spleen Male Medical sciences Middle Aged Pharmacology. Drug treatments phase III randomized controlled trial Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system tacrolimus Tacrolimus - administration & dosage Tacrolimus - adverse effects Tacrolimus - blood Tissue, organ and graft immunology Treatment Outcome
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