Nuclear Factor κB–Mediated Transactivation of Telomerase Prevents Intimal Smooth Muscle Cell From Replicative Senescence During Vascular Repair

OBJECTIVE—To gain insights into mechanisms by which intimal hyperplasia interferes with the repair process by investigating expression and function of the catalytic telomerase reverse transcriptase (TERT) subunit after vascular injury. METHODS AND RESULTS—Functional telomerase is essential to the re...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2010-12, Vol.30 (12), p.2604-2610
Hauptverfasser:	Bu, De-xiu, Johansson, Maria E, Ren, Jingyi, Xu, Da-wei, Johnson, F. Brad, Edfeldt, Kristina, Yan, Zhong-qun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood vessels and receptors Cardiology. Vascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Fundamental and applied biological sciences. Psychology Medical sciences Vertebrates: cardiovascular system
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