Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation – a double‐blind study

Aliment Pharmacol Ther 2011; 34: 41–50 Summary Background One half of patients with constipation are not satisfied with available therapies, hence there is a need for more effective and well‐tolerated drugs. Aim To evaluate the effects of a specific inhibitor of the Ileal Bile Acid Transporter (IB...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2011-07, Vol.34 (1), p.41-50
Hauptverfasser:	Simrén, M., Bajor, A., Gillberg, P.‐G., Rudling, M., Abrahamsson, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged antagonists & inhibitors Biological and medical sciences Cholesterol Cholesterol, LDL - pharmacology Chronic Disease Colon Colon - drug effects Constipation Constipation - drug therapy Defecation Defecation - drug effects Digestive system Double-Blind Method drug effects drug therapy Female Gastroenterologi och hepatologi Gastroenterology and Hepatology Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Transit Gastrointestinal Transit - drug effects Humans LDL Male Medical sciences Middle Aged Organic Anion Transporters Organic Anion Transporters, Sodium-Dependent - antagonists & inhibitors Organic Anion Transporters, Sodium-Dependent - pharmacology Other diseases. Semiology Patient Satisfaction pharmacology Pharmacology. Drug treatments Placebo Effect Sodium-Dependent Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Symporters Symporters - antagonists & inhibitors Symporters - pharmacology Treatment Outcome
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