Podocin-Green Fluorescence Protein Allows Visualization and Functional Analysis of Podocytes

Podocytes do not remain fully differentiated when cultured, and they are difficult to image in vivo, making the study of podocyte biology challenging. Zebrafish embryos are transparent and develop a single, midline, pronephric glomerulus accessible for imaging and systematic functional analysis. Her...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2011-06, Vol.22 (6), p.1019-1023
Hauptverfasser:	BING HE, EBARASI, Lwaki, HULTENBY, Kjell, TRYGGVASON, Karl, BETSHOLTZ, Christer
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Biological and medical sciences Brief Communications Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Kidney Glomerulus - cytology Kidney Glomerulus - metabolism Kidney Glomerulus - ultrastructure Medical sciences Membrane Proteins - genetics Membrane Proteins - metabolism Microscopy, Electron, Scanning Models, Animal Nephrology. Urinary tract diseases Podocytes - cytology Podocytes - metabolism Podocytes - ultrastructure Zebrafish Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
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