A prokaryotic acyl-CoA reductase performing reduction of fatty acyl-CoA to fatty alcohol

► A prokaryotic enzyme (Maqu_2220) is shown to reduce fatty acyl-CoA to fatty alcohol. ► Maqu_2220 can utilize a broad range of acyl-CoA as substrates. ► Maqu_2220 can utilize ACP bound acyl chain as substrate. ► Homologous sequences to Maqu_2220 are found in a narrow range of prokaryotic genera. ►...

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Veröffentlicht in:	FEBS Letters 2011-11, Vol.585 (22), p.3538-3543
Hauptverfasser:	Hofvander, Per, Doan, Thuy T.P., Hamberg, Mats
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Coenzyme A - metabolism Acyl-CoA reductase Aldehyde Oxidoreductases - chemistry Aldehyde Oxidoreductases - metabolism Aldehyde reductase Bacterial Proteins - chemistry Bacterial Proteins - metabolism Fatty alcohol Fatty Alcohols - metabolism Fatty aldehyde Marinobacter - enzymology Marinobacter - metabolism Marinobacter aquaeolei Organic Chemistry Organisk kemi Oxidation-Reduction Phylogeny
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