Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials

Summary Background Moderate differences in efficacy between adjuvant chemotherapy regimens for breast cancer are plausible, and could affect treatment choices. We sought any such differences. Methods We undertook individual-patient-data meta-analyses of the randomised trials comparing: any taxane-pl...

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Veröffentlicht in:	The Lancet (British edition) 2012-02, Vol.379 (9814), p.432-444
Hauptverfasser:	Peto, R, Davies, C, Godwin, J, Gray, R, Pan, H C, Clarke, M, Cutter, D, Darby, S, McGale, P, Taylor, C, Wang, Y C, Bergh, J, Di Leo, A, Albain, K, Swain, S, Piccart, M, Pritchard, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthracyclines - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences biomedical research Breast cancer breast neoplasms Breast Neoplasms - drug therapy Breast Neoplasms - mortality Cancer and Oncology Cancer och onkologi Cancer therapies Chemotherapy Chemotherapy, Adjuvant Clinical Medicine cyclophosphamide cytotoxicity Endocrine therapy epirubicin estrogen receptors Female fluorouracil Gene expression General aspects Gynecology. Andrology. Obstetrics heart Humans immunohistochemistry Internal Medicine Klinisk medicin Mammary gland diseases Medical and Health Sciences Medical research Medical sciences Medicin och hälsovetenskap Meta-analysis methotrexate Miscellaneous Mortality Neoplasm Recurrence, Local patients Public health. Hygiene Public health. Hygiene-occupational medicine Randomized Controlled Trials as Topic risk Stem cells Survival Rate tamoxifen taxanes Taxoids - administration & dosage Tumors women Womens health
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