Rapid Salvage Treatment With Virus-Specific T Cells for Therapy-Resistant Disease

Background. Viral infections are major complications after allogeneic hematopoietic stem cell transplantation (HSCT). During posttransplant immunosuppression the regular T-cell control is compromised. Even if treatment strategies against infections caused by herpes viruses such as cytomegalovirus, E...

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Veröffentlicht in:	Clinical infectious diseases 2012-10, Vol.55 (8), p.1064-1073
Hauptverfasser:	Uhlin, Michael, Gertow, Jens, Uzunel, Mehmet, Okas, Mantas, Berglund, Sofia, Watz, Emma, Brune, Mats, Ljungman, Per, Maeurer, Mark, Mattsson, Jonas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adoptive Transfer - methods Adult Antivirals ARTICLES AND COMMENTARIES Biological and medical sciences Blood Child, Preschool Chimerism Cytomegalovirus Cytotoxicity Disease risk DNA Virus Infections - immunology DNA Virus Infections - therapy DNA Viruses - immunology Epitopes, T-Lymphocyte - immunology Epstein Barr virus infections Family Female Flow Cytometry Graft vs Host Disease Hematopoietic Stem Cell Transplantation - adverse effects Herpes viruses HLA Antigens - blood HLA Antigens - classification Humans Infant Infections Infectious diseases Male Medical sciences Medical treatment Middle Aged Salvage Therapy - methods T cell receptors T lymphocytes T-Lymphocytes, Cytotoxic - cytology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - transplantation Transplantation Transplants & implants Viruses
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