Validation of a Radiosensitivity Molecular Signature in Breast Cancer

Previously, we developed a radiosensitivity molecular signature [radiosensitivity index (RSI)] that was clinically validated in 3 independent datasets (rectal, esophageal, and head and neck) in 118 patients. Here, we test RSI in radiotherapy (RT)-treated breast cancer patients. RSI was tested in 2 p...

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Veröffentlicht in:	Clinical cancer research 2012-09, Vol.18 (18), p.5134-5143
Hauptverfasser:	ESCHRICH, Steven A, FULP, William J, BERGH, Jonas, TORRES-ROCA, Javier F, PAWITAN, Yudi, FOEKENS, John A, SMID, Marcel, MARTENS, John W. M, ECHEVARRIA, Michelle, KAMATH, Vidya, LEE, Ji-Hyun, HARRIS, Eleanor E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - radiotherapy Female Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Menopause Middle Aged Neoplasm Staging Pharmacology. Drug treatments Prognosis Radiation Tolerance - genetics Transcriptome Treatment Outcome Tumors
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