Therapy failure resulting from superinfection by a drug-resistant HIV variant

HIV-1-infected patients can be superinfected with additional HIV-1 variants. Therapy failure can be the consequence of an infection with a resistant strain. A patient was diagnosed with a recent HIV-1 infection in April 2005 and subsequently clinically monitored. HIV-1 evolution was studied by popul...

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Veröffentlicht in:	Antiviral therapy 2012-01, Vol.17 (8), p.1621-1625
Hauptverfasser:	PINGEN, Marieke, NOUWEN, Jan L, SCHUTTEN, Martin, BOUCHER, Charles Ab, DINANT, Sander, ALBERT, Jan, MILD, Mattias, BRODIN, Johanna, SIMEN, Birgitte B, WALSH, Susan, KAYSER, Manfred, DER ENDE, Marchina E.van
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral Therapy, Highly Active Antiviral agents Biological and medical sciences CD4 Lymphocyte Count Drug resistance Drug Resistance, Viral - genetics Evolution Evolutionary genetics Genes, env Genes, pol Genotype HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 - genetics Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Medical sciences Medicin och hälsovetenskap Mutation non-nucleoside reverse transcriptase inhibitors Pharmacology. Drug treatments Phylogeny pol gene Population studies Risk factors Risk groups Superinfection Superinfection - virology Treatment Failure Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load
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