MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case-control samples

We studied the use of methyl-CpG binding domain (MBD) protein-enriched genome sequencing (MBD-seq) as a cost-effective screening tool for methylome-wide association studies (MWAS). Because MBD-seq has not yet been applied on a large scale, we first developed and tested a pipeline for data processing...

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