Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort

Objective To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). Methods Individuals aged 19–59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999–2007; n=3029). We retr...

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Veröffentlicht in:Annals of the rheumatic diseases 2014-05, Vol.73 (5), p.845-853
Hauptverfasser: Olofsson, Tor, Petersson, Ingemar F, Eriksson, Jonas K, Englund, Martin, Simard, Julia F, Nilsson, Jan-Åke, Geborek, Pierre, Jacobsson, Lennart T H, Askling, Johan, Neovius, Martin
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container_issue 5
container_start_page 845
container_title Annals of the rheumatic diseases
container_volume 73
creator Olofsson, Tor
Petersson, Ingemar F
Eriksson, Jonas K
Englund, Martin
Simard, Julia F
Nilsson, Jan-Åke
Geborek, Pierre
Jacobsson, Lennart T H
Askling, Johan
Neovius, Martin
description Objective To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). Methods Individuals aged 19–59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999–2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and baseline predictors of total work days lost during 3 years after RA diagnosis were investigated using linear regression. Due to effect modification by baseline work ability (defined as work days lost the month before diagnosis), analyses were stratified into three categories: full=0 work days lost the month before diagnosis; partial=1–29 work days lost; and none=30 work days lost. Results 71% of patients with full baseline work ability still had full work ability after 3 years compared with 36% (p
doi_str_mv 10.1136/annrheumdis-2012-202911
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Methods Individuals aged 19–59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999–2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and baseline predictors of total work days lost during 3 years after RA diagnosis were investigated using linear regression. Due to effect modification by baseline work ability (defined as work days lost the month before diagnosis), analyses were stratified into three categories: full=0 work days lost the month before diagnosis; partial=1–29 work days lost; and none=30 work days lost. Results 71% of patients with full baseline work ability still had full work ability after 3 years compared with 36% (p&lt;0.001) and 18% (p&lt;0.001) of those with partial and no work ability at baseline, respectively. Elevated baseline levels of HAQ and DAS28, higher age, lower education level and unemployment were associated with more work days lost during 3 years in all strata of baseline work ability (all p&lt;0.05). In a separate analysis, more objective variables (ESR, CRP and swollen joints) were not. Generally, the largest regression coefficients were seen for patients with partial baseline work ability. Conclusions Work ability at RA diagnosis was the most important predictor of 3-year sick leave and disability pension. Taking this into account, HAQ, DAS28, age and education level were also significant predictors, whereas ESR and CRP were not.</description><identifier>ISSN: 0003-4967</identifier><identifier>ISSN: 1468-2060</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/annrheumdis-2012-202911</identifier><identifier>PMID: 23520035</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>England: Elsevier Limited</publisher><subject>Adolescent ; Adult ; Age ; Arthritis ; Arthritis, Rheumatoid ; Autoimmunitet och inflammation ; Autoimmunity and Inflammation ; Clinical Medicine ; cohort analysis ; Cohort Studies ; Compensation ; DAS28 ; demography ; Disability ; Disability Evaluation ; Disability pensions ; Disease ; Disease Activity ; Early Rheumatoid Arthritis ; Education ; Epidemiology ; Female ; Health Assessment Questionnaire ; human ; Humans ; Insurance agencies ; Klinisk medicin ; linear regression analysis ; major clinical study ; Male ; Medical and Health Sciences ; medical leave ; Medicin och hälsovetenskap ; Middle Aged ; Outcomes research ; Patients ; pension ; Pensions ; Population ; priority journal ; register ; Reumatologi och inflammation ; Rheumatoid ; rheumatoid arthritis ; Rheumatology ; Rheumatology and Autoimmunity ; Sick Leave ; Sick Leave - statistics &amp; numerical data ; social insurance ; Studies ; Sweden ; unemployment ; Variables ; Variance analysis ; work disability ; Young Adult</subject><ispartof>Annals of the rheumatic diseases, 2014-05, Vol.73 (5), p.845-853</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2014 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b595t-e9f1687831d4202b8eddb6ec46976a4f78aa2e110b289c0652c53f53da08216f3</citedby><cites>FETCH-LOGICAL-b595t-e9f1687831d4202b8eddb6ec46976a4f78aa2e110b289c0652c53f53da08216f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/73/5/845.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/73/5/845.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,776,780,881,3183,23550,27901,27902,77342,77373</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23520035$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://gup.ub.gu.se/publication/214151$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttps://lup.lub.lu.se/record/3627793$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:128973185$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Olofsson, Tor</creatorcontrib><creatorcontrib>Petersson, Ingemar F</creatorcontrib><creatorcontrib>Eriksson, Jonas K</creatorcontrib><creatorcontrib>Englund, Martin</creatorcontrib><creatorcontrib>Simard, Julia F</creatorcontrib><creatorcontrib>Nilsson, Jan-Åke</creatorcontrib><creatorcontrib>Geborek, Pierre</creatorcontrib><creatorcontrib>Jacobsson, Lennart T H</creatorcontrib><creatorcontrib>Askling, Johan</creatorcontrib><creatorcontrib>Neovius, Martin</creatorcontrib><title>Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort</title><title>Annals of the rheumatic diseases</title><addtitle>Ann Rheum Dis</addtitle><description>Objective To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). Methods Individuals aged 19–59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999–2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and baseline predictors of total work days lost during 3 years after RA diagnosis were investigated using linear regression. Due to effect modification by baseline work ability (defined as work days lost the month before diagnosis), analyses were stratified into three categories: full=0 work days lost the month before diagnosis; partial=1–29 work days lost; and none=30 work days lost. Results 71% of patients with full baseline work ability still had full work ability after 3 years compared with 36% (p&lt;0.001) and 18% (p&lt;0.001) of those with partial and no work ability at baseline, respectively. Elevated baseline levels of HAQ and DAS28, higher age, lower education level and unemployment were associated with more work days lost during 3 years in all strata of baseline work ability (all p&lt;0.05). In a separate analysis, more objective variables (ESR, CRP and swollen joints) were not. Generally, the largest regression coefficients were seen for patients with partial baseline work ability. Conclusions Work ability at RA diagnosis was the most important predictor of 3-year sick leave and disability pension. Taking this into account, HAQ, DAS28, age and education level were also significant predictors, whereas ESR and CRP were not.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Arthritis</subject><subject>Arthritis, Rheumatoid</subject><subject>Autoimmunitet och inflammation</subject><subject>Autoimmunity and Inflammation</subject><subject>Clinical Medicine</subject><subject>cohort analysis</subject><subject>Cohort Studies</subject><subject>Compensation</subject><subject>DAS28</subject><subject>demography</subject><subject>Disability</subject><subject>Disability Evaluation</subject><subject>Disability pensions</subject><subject>Disease</subject><subject>Disease Activity</subject><subject>Early Rheumatoid Arthritis</subject><subject>Education</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Health Assessment Questionnaire</subject><subject>human</subject><subject>Humans</subject><subject>Insurance agencies</subject><subject>Klinisk medicin</subject><subject>linear regression analysis</subject><subject>major clinical study</subject><subject>Male</subject><subject>Medical and Health Sciences</subject><subject>medical leave</subject><subject>Medicin och hälsovetenskap</subject><subject>Middle Aged</subject><subject>Outcomes research</subject><subject>Patients</subject><subject>pension</subject><subject>Pensions</subject><subject>Population</subject><subject>priority journal</subject><subject>register</subject><subject>Reumatologi och inflammation</subject><subject>Rheumatoid</subject><subject>rheumatoid arthritis</subject><subject>Rheumatology</subject><subject>Rheumatology and Autoimmunity</subject><subject>Sick Leave</subject><subject>Sick Leave - statistics &amp; numerical data</subject><subject>social insurance</subject><subject>Studies</subject><subject>Sweden</subject><subject>unemployment</subject><subject>Variables</subject><subject>Variance analysis</subject><subject>work disability</subject><subject>Young Adult</subject><issn>0003-4967</issn><issn>1468-2060</issn><issn>1468-2060</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNksuKFDEUhgtRnHb0FTTgxk1p7pVayjBeoEEXug5JVdKdnqpKmaQYGly48UV9Ek9fHERQXOR28p0_J8lfVc8IfkkIk6_MNKWtW8Y-5JpiQqGjLSH3qhXhUsFK4vvVCmPMat7K5qJ6lPMOllgR9bC6oExQ2BOr6uvH5PrQlZgyih7dxnSDQNTYMISyR_2SwrRBZeuQDykXxH58-753Bmjji0vAms0Uc8goTMigyZQQJzOgY3WmxNAjk8o2hXJEOjcfANTFbUzlcfXAmyG7J-fxsvr85vrT1bt6_eHt-6vX69qKVpTatZ5I1ShGeg73tMr1vZWu47JtpOG-UcZQRwi2VLUdloJ2gnnBeoMVJdKzy6o-6eZbNy9WzymMJu11NEGfQzcwc1oweLgW-PVf-WGZoVlohwTfSYJ7Z7SCczT3QmrLldXCWcpJa0lL6D-P34AchDZHNUo4EQT4Fyd-TvHL4nLRY8idGwYzubhkDQznTFJ-kH7-B7qLS4IPAKppmhY3TDZANSeqSzHn5PxdCQTrg5_0b37SBz_pk58g8-lZf7Gj6-_yfhkIAHoC7Lj7b9Wf97PdTQ</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Olofsson, Tor</creator><creator>Petersson, Ingemar F</creator><creator>Eriksson, Jonas K</creator><creator>Englund, Martin</creator><creator>Simard, Julia F</creator><creator>Nilsson, Jan-Åke</creator><creator>Geborek, Pierre</creator><creator>Jacobsson, Lennart T H</creator><creator>Askling, Johan</creator><creator>Neovius, Martin</creator><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>F1U</scope><scope>D95</scope></search><sort><creationdate>20140501</creationdate><title>Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort</title><author>Olofsson, Tor ; Petersson, Ingemar F ; Eriksson, Jonas K ; Englund, Martin ; Simard, Julia F ; Nilsson, Jan-Åke ; Geborek, Pierre ; Jacobsson, Lennart T H ; Askling, Johan ; Neovius, Martin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b595t-e9f1687831d4202b8eddb6ec46976a4f78aa2e110b289c0652c53f53da08216f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Arthritis</topic><topic>Arthritis, Rheumatoid</topic><topic>Autoimmunitet och inflammation</topic><topic>Autoimmunity and Inflammation</topic><topic>Clinical Medicine</topic><topic>cohort analysis</topic><topic>Cohort Studies</topic><topic>Compensation</topic><topic>DAS28</topic><topic>demography</topic><topic>Disability</topic><topic>Disability Evaluation</topic><topic>Disability pensions</topic><topic>Disease</topic><topic>Disease Activity</topic><topic>Early Rheumatoid Arthritis</topic><topic>Education</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Health Assessment Questionnaire</topic><topic>human</topic><topic>Humans</topic><topic>Insurance agencies</topic><topic>Klinisk medicin</topic><topic>linear regression analysis</topic><topic>major clinical study</topic><topic>Male</topic><topic>Medical and Health Sciences</topic><topic>medical leave</topic><topic>Medicin och hälsovetenskap</topic><topic>Middle Aged</topic><topic>Outcomes research</topic><topic>Patients</topic><topic>pension</topic><topic>Pensions</topic><topic>Population</topic><topic>priority journal</topic><topic>register</topic><topic>Reumatologi och inflammation</topic><topic>Rheumatoid</topic><topic>rheumatoid arthritis</topic><topic>Rheumatology</topic><topic>Rheumatology and Autoimmunity</topic><topic>Sick Leave</topic><topic>Sick Leave - statistics &amp; 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Methods Individuals aged 19–59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999–2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and baseline predictors of total work days lost during 3 years after RA diagnosis were investigated using linear regression. Due to effect modification by baseline work ability (defined as work days lost the month before diagnosis), analyses were stratified into three categories: full=0 work days lost the month before diagnosis; partial=1–29 work days lost; and none=30 work days lost. Results 71% of patients with full baseline work ability still had full work ability after 3 years compared with 36% (p&lt;0.001) and 18% (p&lt;0.001) of those with partial and no work ability at baseline, respectively. Elevated baseline levels of HAQ and DAS28, higher age, lower education level and unemployment were associated with more work days lost during 3 years in all strata of baseline work ability (all p&lt;0.05). In a separate analysis, more objective variables (ESR, CRP and swollen joints) were not. Generally, the largest regression coefficients were seen for patients with partial baseline work ability. Conclusions Work ability at RA diagnosis was the most important predictor of 3-year sick leave and disability pension. Taking this into account, HAQ, DAS28, age and education level were also significant predictors, whereas ESR and CRP were not.</abstract><cop>England</cop><pub>Elsevier Limited</pub><pmid>23520035</pmid><doi>10.1136/annrheumdis-2012-202911</doi><tpages>9</tpages></addata></record>
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subjects Adolescent
Adult
Age
Arthritis
Arthritis, Rheumatoid
Autoimmunitet och inflammation
Autoimmunity and Inflammation
Clinical Medicine
cohort analysis
Cohort Studies
Compensation
DAS28
demography
Disability
Disability Evaluation
Disability pensions
Disease
Disease Activity
Early Rheumatoid Arthritis
Education
Epidemiology
Female
Health Assessment Questionnaire
human
Humans
Insurance agencies
Klinisk medicin
linear regression analysis
major clinical study
Male
Medical and Health Sciences
medical leave
Medicin och hälsovetenskap
Middle Aged
Outcomes research
Patients
pension
Pensions
Population
priority journal
register
Reumatologi och inflammation
Rheumatoid
rheumatoid arthritis
Rheumatology
Rheumatology and Autoimmunity
Sick Leave
Sick Leave - statistics & numerical data
social insurance
Studies
Sweden
unemployment
Variables
Variance analysis
work disability
Young Adult
title Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort
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