Genetic variation in AKT1, PTEN and the 8q24 locus, and the risk of testicular germ cell tumor

STUDY QUESTION Is there an association between testicular germ cell tumor (TGCT) and genetic polymorphisms in AKT1, PTEN and the 8q24 locus? SUMMARY ANSWER Our findings suggest that genetic variation in PTEN may influence the risk of TGCT. WHAT IS KNOWN ALREADY There is strong evidence that genetic...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Human reproduction (Oxford) 2013-07, Vol.28 (7), p.1995-2002
Hauptverfasser:	Andreassen, K.E., Kristiansen, W., Karlsson, R., Aschim, E.L., Dahl, O., Fosså, S.D., Adami, H.-O., Wiklund, F., Haugen, T.B., Grotmol, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomes, Human, Pair 8 - genetics Genetic Association Studies Genetic Predisposition to Disease Humans Male Neoplasms, Germ Cell and Embryonal - genetics Norway Odds Ratio Polymorphism, Single Nucleotide Proto-Oncogene Proteins c-akt - genetics PTEN Phosphohydrolase - genetics Sweden Testicular Neoplasms - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!