Mass Spectrometry-Based Proteomics Identifies UPF1 as a Critical Gene Expression Regulator in MonoMac 6 Cells

5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes, a group of inflammatory lipid mediators derived from arachidonic acid. Recently, we have demonstrated that 5-LO mRNA expression is regulated by alternative splicing and nonsense-mediated mRNA decay (NMD). In a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of proteome research 2013-06, Vol.12 (6), p.2622-2629
Hauptverfasser:	Ochs, Meike J, Ossipova, Elena, Oliynyk, Ganna, Steinhilber, Dieter, Suess, Beatrix, Jakobsson, Per-Johan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Arachidonate 5-Lipoxygenase - genetics Arachidonate 5-Lipoxygenase - metabolism Calcitriol - pharmacology Cell Differentiation - drug effects Cell Line Gene Expression Regulation - drug effects Gene Knockdown Techniques Humans Microsomes - drug effects Microsomes - metabolism Monocytes - cytology Monocytes - drug effects Monocytes - metabolism Nonsense Mediated mRNA Decay Protein Biosynthesis - drug effects Proteomics Tandem Mass Spectrometry Trans-Activators - genetics Trans-Activators - metabolism Transforming Growth Factor beta - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!