The 6-minute walk test and other clinical endpoints in duchenne muscular dystrophy: Reliability, concurrent validity, and minimal clinically important differences from a multicenter study

ABSTRACT Introduction: An international clinical trial enrolled 174 ambulatory males ≥5 years old with nonsense mutation Duchenne muscular dystrophy (nmDMD). Pretreatment data provide insight into reliability, concurrent validity, and minimal clinically important differences (MCIDs) of the 6‐minute...

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Veröffentlicht in:	Muscle & nerve 2013-09, Vol.48 (3), p.357-368
Hauptverfasser:	McDonald, Craig M., Henricson, Erik K., Abresch, R. Ted, Florence, Julaine, Eagle, Michelle, Gappmaier, Eduard, Glanzman, Allan M., Spiegel, Robert, Barth, Jay, Elfring, Gary, Reha, Allen, Peltz, Stuart W.
Format:	Artikel
Sprache:	eng
Schlagworte:	6-minute walk test ambulation Annan medicin och hälsovetenskap diagnosis Disease Progression drug effects drug therapy Duchenne Duchenne muscular dystrophy energy expenditure index Exercise Test Heart Rate Heart Rate - drug effects Heart Rate - physiology Humans Main Male Muscular Dystrophy Muscular Dystrophy, Duchenne - diagnosis Muscular Dystrophy, Duchenne - drug therapy Muscular Dystrophy, Duchenne - physiopathology myometry natural history Other Medical and Health Sciences Outcome Assessment, Health Care Oxadiazoles Oxadiazoles - therapeutic use PedsQL physiology physiopathology Reproducibility of Results therapeutic use Time Factors timed function test Validity Walking Walking - physiology
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