Heritability and the Equal Environments Assumption: Evidence from Multiple Samples of Misclassified Twins

Classically derived estimates of heritability from twin models have been plagued by the possibility of genetic-environmental covariance. Survey questions that attempt to measure directly the extent to which more genetically similar kin (such as monozygotic twins) also share more similar environmenta...

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Veröffentlicht in:Behavior genetics 2013-09, Vol.43 (5), p.415-426
Hauptverfasser: Conley, Dalton, Rauscher, Emily, Dawes, Christopher, Magnusson, Patrik K. E., Siegal, Mark L.
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container_end_page 426
container_issue 5
container_start_page 415
container_title Behavior genetics
container_volume 43
creator Conley, Dalton
Rauscher, Emily
Dawes, Christopher
Magnusson, Patrik K. E.
Siegal, Mark L.
description Classically derived estimates of heritability from twin models have been plagued by the possibility of genetic-environmental covariance. Survey questions that attempt to measure directly the extent to which more genetically similar kin (such as monozygotic twins) also share more similar environmental conditions represent poor attempts to gauge a complex underlying phenomenon of GE-covariance. The present study exploits a natural experiment to address this issue: Self-misperception of twin zygosity in the National Longitudinal Survey of Adolescent Health (Add Health). Such twins were reared under one “environmental regime of similarity” while genetically belonging to another group, reversing the typical GE-covariance and allowing bounded estimates of heritability for a range of outcomes. In addition, we examine twins who were initially misclassified by survey assignment—a stricter standard—in three datasets: Add Health, the Minnesota Twin Family Study and the Child and Adolescent Twin Study in Sweden. Results are similar across approaches and datasets and largely support the validity of the equal environments assumption.
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subjects Adolescent
Adolescents
Attention Deficit Disorder with Hyperactivity - genetics
Attention Deficit Disorder with Hyperactivity - psychology
Behavioral Science and Psychology
Body Mass Index
Child
Children
Clinical Psychology
Depression - genetics
Depression - psychology
Estimates
Family Research
Female
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Health
Health Psychology
Heritability
Humans
Hälsovetenskap
Male
Medicin och hälsovetenskap
Medicinsk genetik
Medicinska och farmaceutiska grundvetenskaper
Minnesota
Original Research
Psychology
Public Health
Social Environment
Sociology
Sweden
Twin studies
Twins
Twins, Dizygotic - genetics
Twins, Dizygotic - psychology
Twins, Monozygotic - genetics
Twins, Monozygotic - psychology
title Heritability and the Equal Environments Assumption: Evidence from Multiple Samples of Misclassified Twins
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