Cord Blood Mesenchymal Stem Cells Suppress DC-T Cell Proliferation via Prostaglandin B2

Immune suppression is a very stable property of multipotent stromal cells also known as mesenchymal stem cells (MSCs). All cell lines tested showed robust immune suppression not affected by a long culture history. Several mechanisms were described to account for this capability. Since several of the...

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Veröffentlicht in:	Stem cells and development 2014-07, Vol.23 (14), p.1582-1593
Hauptverfasser:	van den Berk, Lieke C.J., Jansen, Bas J.H., Snowden, Stuart, Siebers-Vermeulen, Kim G.C., Gilissen, Christian, Kögler, Gesine, Figdor, Carl G., Wheelock, Craig E., Torensma, Ruurd
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation - genetics Coculture Techniques Dendritic Cells - immunology Dendritic Cells - pathology Fetal Blood - immunology HLA Antigens - immunology HLA Antigens - metabolism Humans Immunosuppression Mesenchymal Stromal Cells - immunology Mesenchymal Stromal Cells - pathology Original Research Reports Prostaglandins B - immunology Prostaglandins B - metabolism T-Lymphocytes - immunology T-Lymphocytes - pathology
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