Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients

Next-generation sequencing studies on diffuse large B-cell lymphomas (DLBCLs) have revealed novel targets of genetic aberrations but also high intercohort heterogeneity. Previous studies have suggested that the prevalence of disease subgroups and cytogenetic profiles differ between Western and Asian...

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Veröffentlicht in:	Blood 2014-10, Vol.124 (16), p.2544-2553
Hauptverfasser:	de Miranda, Noel F.C.C., Georgiou, Konstantinos, Chen, Longyun, Wu, Chenglin, Gao, Zhibo, Zaravinos, Apostolos, Lisboa, Susana, Enblad, Gunilla, Teixeira, Manuel R., Zeng, Yixin, Peng, Roujun, Pan-Hammarström, Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Asians - genetics China - epidemiology Exome Female Genetic Heterogeneity High-Throughput Nucleotide Sequencing Humans Lymphoid Neoplasia Lymphoma, Large B-Cell, Diffuse - epidemiology Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - metabolism Male Middle Aged Mutation Receptors, Notch - metabolism Signal Transduction Ubiquitin-Protein Ligases - genetics
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