Breast cancer risk and possible mechanisms of radiation-induced genomic instability in the Swedish hemangioma cohort after reanalyzed dosimetry

•Breast cancer risk analyzed after reestimation of radiation exposure at infant age.•Risk estimates, after new dose calculations, increased compared to previous analyses.•Models of genomic instability were developed and applied to the cohort data.•A radiation-induced transition towards genomic insta...

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Veröffentlicht in:	Mutation research 2015-05, Vol.775, p.1-9
Hauptverfasser:	Eidemüller, Markus, Holmberg, Erik, Jacob, Peter, Lundell, Marie, Karlsson, Per
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Breast cancer risk Breast Neoplasms - epidemiology Female Genomic Instability - radiation effects Hemangioma - epidemiology Hemangioma - radiotherapy Humans Incidence Middle Aged Models of carcinogenesis Models, Biological Neoplasms, Radiation-Induced - epidemiology Radiation Dosage Radiation-induced genomic instability Retrospective Studies Risk Factors Sweden - epidemiology
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