Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues

Natural killer (NK) cells are cytotoxic lymphocytes and play a vital role in controlling viral infections and cancer. In contrast to B and T lymphopoiesis where cellular and regulatory pathways have been extensively characterized, the cellular stages of early human NK cell commitment remain poorly u...

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Veröffentlicht in:	Immunity 2015-08, Vol.43 (2), p.394-407
Hauptverfasser:	Renoux, Virginie M., Zriwil, Alya, Peitzsch, Claudia, Michaëlsson, Jakob, Friberg, Danielle, Soneji, Shamit, Sitnicka, Ewa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens, CD - metabolism Basic Medicine Blood Bone marrow Cancer Cell Differentiation Cell Lineage Cytokines Cytotoxicity Cytotoxicity, Immunologic Fetal Blood - cytology Fetal Development Fetus - cytology Gene amplification Gene expression Hematopoiesis - immunology Humans Immunity, Innate Immunologi inom det medicinska området Immunology in the medical area Immunophenotyping Killer Cells, Natural - physiology Lymphoid Progenitor Cells - physiology Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Tumor necrosis factor-TNF Umbilical cord
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