Baseline symptom severity predicts serotonin transporter change during psychotherapy in patients with major depression

Aims The role of the serotonin transporter (SERT) in the pathophysiology of depression is unclear and only a few follow‐up studies exist. Our aim was to measure changes in SERT availability during psychodynamic psychotherapy in patients with major depression over a follow‐up time of 12 or 18 months....

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Veröffentlicht in:	Psychiatry and clinical neurosciences 2016-01, Vol.70 (1), p.34-41
Hauptverfasser:	Joensuu, Mikko, Ahola, Pasi, Knekt, Paul, Lindfors, Olavi, Saarinen, Pirjo, Tolmunen, Tommi, Valkonen‐Korhonen, Minna, Vanninen, Ritva, Jääskeläinen, Tuija, Virtala, Esa, Kuikka, Jyrki, Tiihonen, Jari, Lehtonen, Johannes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cocaine - analogs & derivatives Cocaine - metabolism Depressive Disorder, Major - diagnosis Depressive Disorder, Major - metabolism Depressive Disorder, Major - psychology Depressive Disorder, Major - therapy Female follow‐up Humans Iodine Radioisotopes - metabolism Male Mental depression Mesencephalon - drug effects Mesencephalon - metabolism midbrain Neuroimaging psychodynamic psychotherapy Psychotherapy Psychotherapy, Psychodynamic Radioligand Assay serial single‐photon emission tomography Serotonin Plasma Membrane Transport Proteins - metabolism serotonin transporter Severity of Illness Index Tomography, Emission-Computed, Single-Photon Young Adult
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