Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression

Variants in the gene encoding the enzyme glutamic acid decarboxylase like 1 (GADL1) have been associated with response to lithium therapy. Both GADL1 and the related enzyme cysteine sulfinic acid decarboxylase (CSAD) have been proposed to be involved in the pyridoxal-5′-phosphate (PLP)-dependent bio...

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Veröffentlicht in:	Neurochemistry international 2015-11, Vol.90, p.173-184
Hauptverfasser:	Winge, Ingeborg, Teigen, Knut, Fossbakk, Agnete, Mahootchi, Elaheh, Kleppe, Rune, Sköldberg, Filip, Kämpe, Olle, Haavik, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspartate Brain Brain - metabolism Carboxy-Lyases - metabolism Cysteine sulfinic acid decarboxylase Humans Lithium Mice Neurons - metabolism Pyridoxal-phosphate RNA, Messenger - metabolism Taurine Taurine - chemistry Taurine - metabolism
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