A Randomized Trial of Low-Cost Mesh in Groin Hernia Repair
This trial in Uganda compared commercial mesh with a low-cost mesh (sterilized mosquito mesh) for groin hernia repair. There were no significant differences between groups in the rate of hernia recurrence after 1 year or in the frequency of postoperative complications. Repair of a groin hernia is on...
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| Veröffentlicht in: | The New England journal of medicine 2016-01, Vol.374 (2), p.146-153 |
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| container_title | The New England journal of medicine |
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| creator | Löfgren, Jenny Nordin, Pär Ibingira, Charles Matovu, Alphonsus Galiwango, Edward Wladis, Andreas |
| description | This trial in Uganda compared commercial mesh with a low-cost mesh (sterilized mosquito mesh) for groin hernia repair. There were no significant differences between groups in the rate of hernia recurrence after 1 year or in the frequency of postoperative complications.
Repair of a groin hernia is one of the most frequently performed surgical procedures worldwide, with approximately 20 million operations performed annually.
1
–
3
Groin hernia causes considerable illness and even death if left untreated, and its repair has been identified as a key intervention to reduce the burden of disease in low- and middle-income countries.
1
,
4
–
9
Surgery in general and groin hernia repair in particular have also been shown to be highly cost-effective, even in comparison with other prioritized health care interventions such as child vaccination and treatment of human immunodeficiency virus infection in such settings.
10
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Resource constraints, . . . |
| doi_str_mv | 10.1056/NEJMoa1505126 |
| format | Article |
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Repair of a groin hernia is one of the most frequently performed surgical procedures worldwide, with approximately 20 million operations performed annually.
1
–
3
Groin hernia causes considerable illness and even death if left untreated, and its repair has been identified as a key intervention to reduce the burden of disease in low- and middle-income countries.
1
,
4
–
9
Surgery in general and groin hernia repair in particular have also been shown to be highly cost-effective, even in comparison with other prioritized health care interventions such as child vaccination and treatment of human immunodeficiency virus infection in such settings.
10
,
11
Resource constraints, . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>ISSN: 1533-4406</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa1505126</identifier><identifier>PMID: 26760085</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Adult ; Clinical trials ; Developing Countries ; Double-Blind Method ; Evidence-based medicine ; Follow-Up Studies ; Hernia ; Hernia, Inguinal - surgery ; Hernias ; Herniorrhaphy - economics ; Herniorrhaphy - instrumentation ; Humans ; kirurgi ; Low income groups ; Male ; Medical supplies ; Middle Aged ; Patient Satisfaction ; Postoperative Complications - epidemiology ; Recurrence ; Surgery ; Surgical mesh ; Surgical Mesh - economics ; Uganda</subject><ispartof>The New England journal of medicine, 2016-01, Vol.374 (2), p.146-153</ispartof><rights>Copyright © 2016 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-fe8fc731ebd6deba2959a2d66b578ed70b541a3c8e32e252659829fcce85ab253</citedby><cites>FETCH-LOGICAL-c466t-fe8fc731ebd6deba2959a2d66b578ed70b541a3c8e32e252659829fcce85ab253</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa1505126$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMoa1505126$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>230,314,550,776,780,881,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26760085$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-107657$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:132744885$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Löfgren, Jenny</creatorcontrib><creatorcontrib>Nordin, Pär</creatorcontrib><creatorcontrib>Ibingira, Charles</creatorcontrib><creatorcontrib>Matovu, Alphonsus</creatorcontrib><creatorcontrib>Galiwango, Edward</creatorcontrib><creatorcontrib>Wladis, Andreas</creatorcontrib><title>A Randomized Trial of Low-Cost Mesh in Groin Hernia Repair</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>This trial in Uganda compared commercial mesh with a low-cost mesh (sterilized mosquito mesh) for groin hernia repair. There were no significant differences between groups in the rate of hernia recurrence after 1 year or in the frequency of postoperative complications.
Repair of a groin hernia is one of the most frequently performed surgical procedures worldwide, with approximately 20 million operations performed annually.
1
–
3
Groin hernia causes considerable illness and even death if left untreated, and its repair has been identified as a key intervention to reduce the burden of disease in low- and middle-income countries.
1
,
4
–
9
Surgery in general and groin hernia repair in particular have also been shown to be highly cost-effective, even in comparison with other prioritized health care interventions such as child vaccination and treatment of human immunodeficiency virus infection in such settings.
10
,
11
Resource constraints, . . .</description><subject>Adult</subject><subject>Clinical trials</subject><subject>Developing Countries</subject><subject>Double-Blind Method</subject><subject>Evidence-based medicine</subject><subject>Follow-Up Studies</subject><subject>Hernia</subject><subject>Hernia, Inguinal - surgery</subject><subject>Hernias</subject><subject>Herniorrhaphy - economics</subject><subject>Herniorrhaphy - instrumentation</subject><subject>Humans</subject><subject>kirurgi</subject><subject>Low income groups</subject><subject>Male</subject><subject>Medical supplies</subject><subject>Middle Aged</subject><subject>Patient Satisfaction</subject><subject>Postoperative Complications - epidemiology</subject><subject>Recurrence</subject><subject>Surgery</subject><subject>Surgical mesh</subject><subject>Surgical Mesh - economics</subject><subject>Uganda</subject><issn>0028-4793</issn><issn>1533-4406</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><sourceid>D8T</sourceid><recordid>eNp90c9r2zAUB3AxVpY03XHXYRiDXtw-ydYP7xay_iRpoWS7Ctl-bpXGVirFlPavr0rSjhZWHSQhPnx5eo-QbxQOKHBxeHF0PnOGcuCUiU9kSHmWpXkO4jMZAjCV5rLIBmQ3hAXERfPiCxkwIQWA4kPya5xcma52rX3EOpl7a5aJa5Kpu08nLqyTGYabxHbJiXdxP0XfWZNc4cpYv0d2GrMM-HV7jsif46P55DSdXp6cTcbTtMqFWKcNqqaSGcWyFjWWhhW8MKwWouRSYS2h5Dk1WaUwY8g4E7xQrGiqChU3JePZiKSb3HCPq77UK29b4x-0M1Zvn27jDTUHBfJj_9v-HWvnr3Xf9pqCFFxGv7_xK-_uegxr3dpQ4XJpOnR90DT2SsWGMYj0xzu6cL3v4u-j4hJkDgX8K6DyLgSPzWsJFPTz0PSboUX_fZvaly3Wr_plShH83IC2DbrDRfufoCfQYZts</recordid><startdate>20160114</startdate><enddate>20160114</enddate><creator>Löfgren, Jenny</creator><creator>Nordin, Pär</creator><creator>Ibingira, Charles</creator><creator>Matovu, Alphonsus</creator><creator>Galiwango, Edward</creator><creator>Wladis, Andreas</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>ADHXS</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>D93</scope><scope>ZZAVC</scope></search><sort><creationdate>20160114</creationdate><title>A Randomized Trial of Low-Cost Mesh in Groin Hernia Repair</title><author>Löfgren, Jenny ; Nordin, Pär ; Ibingira, Charles ; Matovu, Alphonsus ; Galiwango, Edward ; Wladis, Andreas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-fe8fc731ebd6deba2959a2d66b578ed70b541a3c8e32e252659829fcce85ab253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Clinical trials</topic><topic>Developing Countries</topic><topic>Double-Blind Method</topic><topic>Evidence-based medicine</topic><topic>Follow-Up Studies</topic><topic>Hernia</topic><topic>Hernia, Inguinal - surgery</topic><topic>Hernias</topic><topic>Herniorrhaphy - economics</topic><topic>Herniorrhaphy - instrumentation</topic><topic>Humans</topic><topic>kirurgi</topic><topic>Low income groups</topic><topic>Male</topic><topic>Medical supplies</topic><topic>Middle Aged</topic><topic>Patient Satisfaction</topic><topic>Postoperative Complications - epidemiology</topic><topic>Recurrence</topic><topic>Surgery</topic><topic>Surgical mesh</topic><topic>Surgical Mesh - economics</topic><topic>Uganda</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Löfgren, Jenny</creatorcontrib><creatorcontrib>Nordin, Pär</creatorcontrib><creatorcontrib>Ibingira, Charles</creatorcontrib><creatorcontrib>Matovu, Alphonsus</creatorcontrib><creatorcontrib>Galiwango, Edward</creatorcontrib><creatorcontrib>Wladis, Andreas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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There were no significant differences between groups in the rate of hernia recurrence after 1 year or in the frequency of postoperative complications.
Repair of a groin hernia is one of the most frequently performed surgical procedures worldwide, with approximately 20 million operations performed annually.
1
–
3
Groin hernia causes considerable illness and even death if left untreated, and its repair has been identified as a key intervention to reduce the burden of disease in low- and middle-income countries.
1
,
4
–
9
Surgery in general and groin hernia repair in particular have also been shown to be highly cost-effective, even in comparison with other prioritized health care interventions such as child vaccination and treatment of human immunodeficiency virus infection in such settings.
10
,
11
Resource constraints, . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>26760085</pmid><doi>10.1056/NEJMoa1505126</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2016-01, Vol.374 (2), p.146-153 |
| issn | 0028-4793 1533-4406 1533-4406 |
| language | eng |
| recordid | cdi_swepub_primary_oai_swepub_ki_se_508075 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; SWEPUB Freely available online; New England Journal of Medicine |
| subjects | Adult Clinical trials Developing Countries Double-Blind Method Evidence-based medicine Follow-Up Studies Hernia Hernia, Inguinal - surgery Hernias Herniorrhaphy - economics Herniorrhaphy - instrumentation Humans kirurgi Low income groups Male Medical supplies Middle Aged Patient Satisfaction Postoperative Complications - epidemiology Recurrence Surgery Surgical mesh Surgical Mesh - economics Uganda |
| title | A Randomized Trial of Low-Cost Mesh in Groin Hernia Repair |
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