In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts

To elucidate processes in the osteoclastic bone resorption, visualise resorption and related actin reorganisation, a combination of imaging technologies and an applicable in vitro model is needed. Nanosized bone powder from matching species is deposited on any biocompatible surface in order to form...

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Veröffentlicht in:	Scientific reports 2016-03, Vol.6 (1), p.22585-22585, Article 22585
Hauptverfasser:	Deguchi, Takahiro, Alanne, Maria H., Fazeli, Elnaz, Fagerlund, Katja M., Pennanen, Paula, Lehenkari, Petri, Hänninen, Pekka E., Peltonen, Juha, Näreoja, Tuomas
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 14/19 14/3 631/1647/245/2226 631/57/2282 631/80/128/1276 631/80/79 692/698/1671/63 Actin Adenosine triphosphatase Adhesion Atomic force microscopy Bone imaging Bone resorption Bone Resorption - metabolism Bone Resorption - pathology Cortical bone Dynamin Female H+-transporting ATPase Humanities and Social Sciences Humans Immunofluorescence Male Microscopy Microscopy, Atomic Force Microscopy, Interference Models, Biological multidisciplinary Osteoclasts Osteoclasts - metabolism Osteoclasts - ultrastructure Powder Reflectance Science Spectroscopy
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