Multiparameter functional diversity of human C2H2 zinc finger proteins

C2H2 zinc finger proteins represent the largest and most enigmatic class of human transcription factors. Their C2H2-ZF arrays are highly variable, indicating that most will have unique DNA binding motifs. However, most of the binding motifs have not been directly determined. In addition, little is k...

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Veröffentlicht in:	Genome research 2016-12, Vol.26 (12), p.1742-1752
Hauptverfasser:	Schmitges, Frank W, Radovani, Ernest, Najafabadi, Hamed S, Barazandeh, Marjan, Campitelli, Laura F, Yin, Yimeng, Jolma, Arttu, Zhong, Guoqing, Guo, Hongbo, Kanagalingam, Tharsan, Dai, Wei F, Taipale, Jussi, Emili, Andrew, Greenblatt, Jack F, Hughes, Timothy R
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites CYS2-HIS2 Zinc Fingers DNA - metabolism Evolution, Molecular Gene Expression Regulation HEK293 Cells Humans Protein Binding Protein Interaction Maps Resource Sequence Analysis, DNA Sequence Analysis, RNA Transcription Factors - chemistry Transcription Factors - genetics Transcription Factors - metabolism
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