A2A‐D2 receptor–receptor interaction modulates gliotransmitter release from striatal astrocyte processes

Evidence for striatal A2A‐D2 heterodimers has led to a new perspective on molecular mechanisms involved in schizophrenia and Parkinson's disease. Despite the increasing recognition of astrocytes’ participation in neuropsychiatric disease vulnerability, involvement of striatal astrocytes in A2A...

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Veröffentlicht in:	Journal of neurochemistry 2017-01, Vol.140 (2), p.268-279
Hauptverfasser:	Cervetto, Chiara, Venturini, Arianna, Passalacqua, Mario, Guidolin, Diego, Genedani, Susanna, Fuxe, Kjell, Borroto‐Esquela, Dasiel O., Cortelli, Pietro, Woods, Amina, Maura, Guido, Marcoli, Manuela, Agnati, Luigi F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - metabolism Animals astrocyte processes Astrocytes - metabolism Cells Corpus Striatum - metabolism glutamate Glutamic Acid - metabolism heterodimers Male Mental disorders Neostriatum - metabolism Neurochemistry Neurological disorders Neurotransmitters Rats, Sprague-Dawley Receptor, Adenosine A2A - metabolism Receptors, Dopamine D2 - metabolism Receptor–receptor interactions Synaptic Transmission - physiology
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