Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging

Multifunctional nanocarriers for controlled drug delivery, imaging of disease development and follow-up of treatment efficacy are promising novel tools for disease diagnosis and treatment. In the current investigation, we present a multifunctional theranostic nanocarrier system for anticancer drug d...

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Veröffentlicht in:	Journal of nanobiotechnology 2016-12, Vol.14 (1), p.82-82, Article 82
Hauptverfasser:	Asem, Heba, Zhao, Ying, Ye, Fei, Barrefelt, Åsa, Abedi-Valugerdi, Manuchehr, El-Sayed, Ramy, El-Serafi, Ibrahim, Abu-Salah, Khalid M, Hamm, Jörg, Muhammed, Mamoun, Hassan, Moustapha
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Animals Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacokinetics Biodegradable polymer Biodistribution Busulfan Busulfan - chemistry Busulfan - pharmacokinetics Busulfan - pharmacology Busulphan Cancer Cell Survival - drug effects Dextrans - chemistry Diagnostic imaging Drug Carriers - chemistry Drug delivery Half-Life HL-60 Cells Humans In vivo fluorescence imaging Liver - metabolism Liver - pathology Lung - metabolism Lung - physiology Magnetic resonance imaging Magnetite Nanoparticles - chemistry Magnetite Nanoparticles - ultrastructure Mice Mice, Inbred BALB C Micelles Nanoparticles Particle Size Physiological aspects Polyesters - chemistry Polyethylene Glycols - chemistry Spleen - metabolism Spleen - pathology Tissue Distribution
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