An Analysis of Two Genome-Wide Association Meta-Analyses Identifies a New Locus for Broad Depression Phenotype

Abstract Background The genetics of depression has been explored in genome-wide association studies that focused on major depressive disorder or depressive symptoms with mostly negative findings. A broad depression phenotype including both phenotypes has not been tested previously using a genome-wid...

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Veröffentlicht in:Biological psychiatry (1969) 2017-09, Vol.82 (5), p.322-329
Hauptverfasser: Direk, Nese, MD, MSc, Williams, Stephanie, ScM, Smith, Jennifer A., PhD, MPH, Ripke, Stephan, MD, PhD, Air, Tracy, BA(Hons , M.Biostatistics, Amare, Azmeraw T., MPH, MSc, Amin, Najaf, PhD, Baune, Bernhard T., MD, PhD, MPH, Bennett, David A., MD, Blackwood, Douglas H.R., MD, PhD, Boomsma, Dorret, PhD, Breen, Gerome, PhD, Buttenschøn, Henriette N., PhD, Byrne, Enda M., PhD, Børglum, Anders D., MD, PhD, Castelao, Enrique, MSc, Cichon, Sven, PhD, Clarke, Toni-Kim, PhD, Cornelis, Marilyn C., PhD, Dannlowski, Udo, MD, PhD, De Jager, Philip L., MD, PhD, Domenici, Enrico, PhD, van Duijn, Cornelia M., PhD, Dunn, Erin C., ScD, MPH, Eriksson, Johan G., MD, DMSc, Esko, Tonu, PhD, Faul, Jessica D., PhD, Ferrucci, Luigi, MD, PhD, Fornage, Myriam, PhD, Geus, Eco de, PhD, Gill, Michael, MD, Gordon, Scott D., PhD, Grabe, Hans Jörgen, MD, Grootheest, Gerard van, MSc, Hamilton, Steven P., MD, PhD, Hartman, Catharina A., PhD, Heath, Andrew C., DPhil, Hek, Karin, PhD, Hofman, Albert, MD, PhD, Homuth, Georg, PhD, Horn, Carsten, PhD, Hottenga, Jouke Jan, PhD, Kardia, Sharon L.R., PhD, Kloiber, Stefan, MD, Koenen, Karestan, PhD, Kutalik, Zoltán, PhD, Ladwig, Karl-Heinz, MD, PhD, Levinson, Douglas F., MD, Lewis, Cathryn M., PhD, Lewis, Glyn, PhD, Li, Qingqin S., PhD, Llewellyn, David J., PhD, Lucae, Susanne, MD, PhD, Lunetta, Kathryn L., PhD, MacIntyre, Donald J., MD, Madden, Pamela, PhD, Martin, Nicholas G., PhD, McIntosh, Andrew M., MD, Metspalu, Andres, MD, PhD, Milaneschi, Yuri, PhD, Montgomery, Grant W., PhD, Mors, Ole, PhD, Mosley, Thomas H., PhD, Murabito, Joanne M., MD, ScM, Müller-Myhsok, Bertram, MD, Nöthen, Markus M., MD, PhD, Nyholt, Dale R., PhD, O’Donovan, Michael C., MD, PhD, Penninx, Brenda W., PhD, Pergadia, Michele L., PhD, Perlis, Roy, MD, MSc, Potash, James B., MD, Preisig, Martin, MD, Purcell, Shaun M., PhD, Quiroz, Jorge A., MD, Räikkönen, Katri, PhD, Rice, John P., PhD, Rietschel, Marcella, MD, PhD, Rivera, Margarita, PhD, Schulze, Thomas G., MD, Shi, Jianxin, PhD, Shyn, Stanley, MD, PhD, Sinnamon, Grant C., PhD, Smit, Johannes H., PhD, Smoller, Jordan W., MD, ScD, Snieder, Harold, PhD, Tanaka, Toshiko, PhD, Tansey, Katherine E., PhD, Teumer, Alexander, PhD, Uher, Rudolf, MD, PhD, Umbricht, Daniel, MD, der Auwera, Sandra Van, Dipl. Biomathematikerin, Ware, Erin B., PhD, Weir, David R., PhD, Weissman, Myrna M., PhD, Willemsen, Gonneke, PhD, Yang, Jingyun, PhD, Zhao, Wei, PhD, Tiemeier, Henning, MD, PhD, Sullivan, Patrick F., MD
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