Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference

ABSTRACTAs pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mec...

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Veröffentlicht in:Journal of pediatric gastroenterology and nutrition 2017-09, Vol.65 (3), p.e53-e59
Hauptverfasser: McLin, Valérie A, Allen, Upton, Boyer, Olivia, Bucuvalas, John, Colledan, Michele, Cuturi, Maria-Cristina, d’Antiga, Lorenzo, Debray, Dominique, Dezsofi, Antal, Goyet, Jean de Ville de, Dhawan, Anil, Durmaz, Ozlem, Falk, Christine, Feng, Sandy, Fischler, Björn, Franchi-Abella, Stéphanie, Frauca, Esteban, Ganschow, Rainer, Gottschalk, Stephen, Hadzic, Nedim, Hierro, Loreto, Horslen, Simon, Hubscher, Stefan, Karam, Vincent, Kelly, Deirdre, Maecker-Kolhoff, Britta, Mazariegos, George, McKiernan, Patrick, Melk, Anette, Nobili, Valerio, Ozgenç, Funda, Reding, Raymond, Sciveres, Marco, Sharif, Khalid, Socha, Piotr, Toso, Christian, Vajro, Pietro, Verma, Anita, Wildhaber, Barbara E, Baumann, Ulrich
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Sprache:eng
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Zusammenfassung:ABSTRACTAs pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and the role of donor-specific antibodies, considering ways to expand donor pool, minimizing long-term side effects of immunosuppression, and fine-tuning surgical techniques to minimize biliary and vascular complications.
ISSN:0277-2116
1536-4801
DOI:10.1097/MPG.0000000000001564